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    Association details:
    Biomarker:ALK G1123S
    Cancer:Non Small Cell Lung Cancer
    Drug:Zykadia (ceritinib) (ALK inhibitor)
    Direction:Resistant
    Evidence:
    Evidence Level:
    Resistant: C4 – Case Studies
    New
    Source:
    J Thorac Oncol
    Title:

    Identification of a Novel ALK G1123S Mutation in a Patient with ALK-rearranged Non–small-cell Lung Cancer Exhibiting Resistance to Ceritinib

    Excerpt:
    In summary, the G1123S mutation was identified in a patient with ALK+ non–small-cell lung cancer exhibiting resistance to ceritinib.
    DOI:
    10.1097/JTO.0000000000000509