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    Association details:
    Biomarker:CTSD positive + ER positive
    Cancer:Breast Cancer
    Drug:tamoxifen (Estrogen receptor antagonist)
    Direction:Resistant
    Evidence:
    Evidence Level:
    Resistant: D – Preclinical
    Source:
    AACR 2022
    Title:

    5495 - PHI-501, a potent and novel inhibitor of NRAS mutated acute myeloid leukemia

    Published date:
    03/09/2022
    Excerpt:
    Cathepsin D positive tumors with ER positive staining who were treated with tamoxifen were associated with lower BCSS...