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    Association details:
    Biomarker:HER-2 negative
    Cancer:Gastroesophageal Junction Adenocarcinoma
    Drug:5-fluorouracil (Thymidylate synthase inhibitor) +
    oxaliplatin (DNA synthesis inhibitor, DNA cross linking agent)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: A2 - Guideline
    Source:
    NCCN
    Published date:
    12/23/2020
    Excerpt:
    Gastroesophageal Junction Adenocarcinoma: Principles of systemic therapy...Preferred regimens…HER2 overexpression negative…Fluoropyrimidine (fluorouracil or capecitabine) and oxaliplatin