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    Association details:
    Biomarker:MCAM expression
    Cancer:Solid Tumor
    Drug:AMT-253 (CAR-T immunotherapy)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: D – Preclinical
    Source:
    Cancer Res
    Title:

    A Cell Surface-Binding Antibody Atlas Nominates a MUC18-Directed Antibody-Drug Conjugate for Targeting Melanoma

    Published date:
    11/15/2023
    Excerpt:
    AMT-253 was also efficacious in a wide range of MUC18-expressing solid tumors.
    DOI:
    10.1158/0008-5472.CAN-23-1356