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    COMPANY:
    Rhythm Pharma

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    Other names: Rhythm Pharmaceuticals Inc | Rhythm Pharmaceuticals | Rhythm Pharmaceuticals, Inc. | Rhythm Pharmaceuticals Inc.
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    Efficacy And Safety Of Setmelanotide In Acquired Hypothalamic Obesity: Results From A Double-blind, Multicenter, Placebo-controlled, Randomized Phase 3 Trial (ENDO 2025)
    P3 | "In the SET arm, there was 1 serious treatment-related AE of hypernatremia due to vomiting and an inability to tolerate their desmopressin. In the largest randomized, PBO-controlled trial in aHO to date, SET demonstrated significant effects over PBO in the primary and all key secondary efficacy endpoints at 52 weeks, with no new safety signals. SET may represent an important treatment option for pts with aHO aged ≥4 y, for which there are no currently approved treatments."
    Clinical • P3 data • Late-breaking abstract