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BIOMARKER:

ALK positive

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Entrez ID:

Related biomarkers:

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ALK rearrangement (43)

ALK mutation (20)

ALK wild-type (18)

STRN-ALK rearrangement (10)

ALK translocation (9)

EGFR wild-type + ALK wild-type (7)

EML4-ALK rearrangement (5)

ALK G1202del (4)

ALK rearrangement + TP53 mutation (4)

TYRO3 mutation + ALK mutation (3)

ALK C1156Y + ALK I1171T (2)

ALK C1156Y + ALK L1198F (2)

ALK F1174L + ALK G1202R (2)

DCTN1-ALK rearrangement + ALK-CLIP4 rearrangement (2)

ALK C1156Y + ALK G1202R (1)

ALK G1202R + ALK F1174L + ALK T1151M (1)

ALK L1152R + EGFR mutation (1)

ALK L1196M + ALK C1156Y (1)

ALK L1196M + ALK G1202R (1)

ALK L1196M + ALK L1198F (1)

ALK L1198F + ALK G1202R (1)

ALK TKD mutation (1)

ALK rearrangement + ALK L1196M + TP53 mutation (1)

ALK rearrangement + ALK R1275Q + TP53 mutation (1)

ALK rearrangement + ALK T1151M + ALK L1198F + EGFR A839V (1)

ALK rearrangement + EGFR D761N + KRAS V14I (1)

ALK rearrangement + HER-2 mutation (1)

ALK rearrangement + KRAS mutation (1)

ALK rearrangement + PIK3CA mutation (1)

ALK rearrangement + TP53 R175H + EGFR A839V + PI3KCA mutation (1)

ALK rearrangement + TP53 wild-type (1)

EGFR L858R + ALK R1275Q (1)

EGFR L858R + ALK rearrangement (1)

EGFR exon 19 deletion + ALK mutation (1)

EGFR mutation + ALK mutation (1)

EGFR wild-type + ALK wild-type + ROS1 wild-type (1)

EGFR wild-type + ALK wild-type + STK11 mutation (1)

EML4-ALK I1171N + EML4-ALK L1196M (1)

EML4-ALK I1171N + EML4-ALK L1196M + EML4-ALK G1202R (1)

LMO7-ALK rearrangement (1)

PLEKHH2-ALK rearrangement (1)

RMST-ALK rearrangement (1)

TP53 G245S + ALK rearrangement (1)

ALK mutation + TP53 mutation (0)

ALK rearrangement (43)

ALK mutation (20)

ALK wild-type (18)

STRN-ALK rearrangement (10)

ALK translocation (9)

EGFR wild-type + ALK wild-type (7)

EML4-ALK rearrangement (5)

ALK G1202del (4)

ALK rearrangement + TP53 mutation (4)

TYRO3 mutation + ALK mutation (3)

ALK C1156Y + ALK I1171T (2)

ALK C1156Y + ALK L1198F (2)

ALK F1174L + ALK G1202R (2)

DCTN1-ALK rearrangement + ALK-CLIP4 rearrangement (2)

ALK C1156Y + ALK G1202R (1)

ALK G1202R + ALK F1174L + ALK T1151M (1)

ALK L1152R + EGFR mutation (1)

ALK L1196M + ALK C1156Y (1)

ALK L1196M + ALK G1202R (1)

ALK L1196M + ALK L1198F (1)

ALK L1198F + ALK G1202R (1)

ALK TKD mutation (1)

ALK rearrangement + ALK L1196M + TP53 mutation (1)

ALK rearrangement + ALK R1275Q + TP53 mutation (1)

ALK rearrangement + ALK T1151M + ALK L1198F + EGFR A839V (1)

ALK rearrangement + EGFR D761N + KRAS V14I (1)

ALK rearrangement + HER-2 mutation (1)

ALK rearrangement + KRAS mutation (1)

ALK rearrangement + PIK3CA mutation (1)

ALK rearrangement + TP53 R175H + EGFR A839V + PI3KCA mutation (1)

ALK rearrangement + TP53 wild-type (1)

EGFR L858R + ALK R1275Q (1)

EGFR L858R + ALK rearrangement (1)

EGFR exon 19 deletion + ALK mutation (1)

EGFR mutation + ALK mutation (1)

EGFR wild-type + ALK wild-type + ROS1 wild-type (1)

EGFR wild-type + ALK wild-type + STK11 mutation (1)

EML4-ALK I1171N + EML4-ALK L1196M (1)

EML4-ALK I1171N + EML4-ALK L1196M + EML4-ALK G1202R (1)

LMO7-ALK rearrangement (1)

PLEKHH2-ALK rearrangement (1)

RMST-ALK rearrangement (1)

TP53 G245S + ALK rearrangement (1)

ALK mutation + TP53 mutation (0)

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Related tests:

VENTANA ALK (D5F3) CDx Assay (13)

VENTANA ALK (D5F3) CDx Assay (13)

ALK positive	Non Small Cell Lung Cancer	ALK positive	Non Small Cell Lung Cancer	lorlatinib Sensitive: A1 - Approval lorlatinib Sensitive : A1	lorlatinib Sensitive: A1 - Approval lorlatinib Sensitive : A1
ALK positive	Non Small Cell Lung Cancer	ALK positive	Non Small Cell Lung Cancer	alectinib Sensitive: A1 - Approval alectinib Sensitive : A1	alectinib Sensitive: A1 - Approval alectinib Sensitive : A1
ALK positive	Non Small Cell Lung Cancer	ALK positive	Non Small Cell Lung Cancer	brigatinib Sensitive: A1 - Approval brigatinib Sensitive : A1	brigatinib Sensitive: A1 - Approval brigatinib Sensitive : A1
ALK positive	Non-Hodgkin’s Lymphoma	ALK positive	Non-Hodgkin’s Lymphoma	crizotinib Sensitive: A1 - Approval crizotinib Sensitive : A1	crizotinib Sensitive: A1 - Approval crizotinib Sensitive : A1
ALK positive	Non Small Cell Lung Cancer	ALK positive	Non Small Cell Lung Cancer	crizotinib Sensitive: A1 - Approval crizotinib Sensitive : A1	crizotinib Sensitive: A1 - Approval crizotinib Sensitive : A1
ALK positive	Non Small Cell Lung Cancer	ALK positive	Non Small Cell Lung Cancer	ensartinib Sensitive: A1 - Approval ensartinib Sensitive : A1	ensartinib Sensitive: A1 - Approval ensartinib Sensitive : A1
ALK positive	Non Small Cell Lung Cancer	ALK positive	Non Small Cell Lung Cancer	bevacizumab + atezolizumab Sensitive: A1 - Approval bevacizumab + atezolizumab Sensitive : A1	bevacizumab + atezolizumab Sensitive: A1 - Approval bevacizumab + atezolizumab Sensitive : A1
ALK positive	Non Small Cell Lung Cancer	ALK positive	Non Small Cell Lung Cancer	ceritinib Sensitive: A1 - Approval ceritinib Sensitive : A1	ceritinib Sensitive: A1 - Approval ceritinib Sensitive : A1
ALK positive	Non Small Cell Lung Cancer	ALK positive	Non Small Cell Lung Cancer	atezolizumab Sensitive: A1 - Approval atezolizumab Sensitive : A1	atezolizumab Sensitive: A1 - Approval atezolizumab Sensitive : A1
ALK positive	Non Small Cell Lung Cancer	ALK positive	Non Small Cell Lung Cancer	iruplinalkib Sensitive: A1 - Approval iruplinalkib Sensitive : A1	iruplinalkib Sensitive: A1 - Approval iruplinalkib Sensitive : A1
ALK positive	Non-Hodgkin’s Lymphoma	ALK positive	Non-Hodgkin’s Lymphoma	alectinib Sensitive: A2 - Guideline alectinib Sensitive : A2	alectinib Sensitive: A2 - Guideline alectinib Sensitive : A2
ALK positive	Peripheral T-cell Lymphoma	ALK positive	Peripheral T-cell Lymphoma	crizotinib Sensitive: A2 - Guideline crizotinib Sensitive : A2	crizotinib Sensitive: A2 - Guideline crizotinib Sensitive : A2