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BIOMARKER:
BRAF G469V
i
Other names:
BRAF, B-raf proto-oncogene, B-raf proto-oncogene, Serine/threonine kinase, V-Raf murine sarcoma viral oncogene homolog B, Serine/threonine-protein kinase B-Raf, Proto-oncogene B-Raf, BRAF1, RAFB1, B-raf proto-oncogene Serine/threonine-protein kinase, Murine sarcoma viral (V-Raf) oncogene homolog B1, B-raf serine/threonine-protein, 94 KDa B-raf protein, B-RAF1
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Entrez ID:
673
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
BRAF L485-P490 deletion (6)
BRAF amplification (1)
BRAF L485-P490 deletion (6)
BRAF amplification (1)
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Associations
News
Trials
VERI cancer hierarchy
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BRAF G469V
Solid Tumor
BRAF G469V
Solid Tumor
BVD-523
Sensitive: B - Late Trials
BVD-523
Sensitive
:
B
BVD-523
Sensitive: B - Late Trials
BVD-523
Sensitive
:
B
BRAF G469V
Non Small Cell Lung Cancer
BRAF G469V
Non Small Cell Lung Cancer
trametinib + dabrafenib
Resistant: C3 – Early Trials
trametinib + dabrafenib
Resistant
:
C3
trametinib + dabrafenib
Resistant: C3 – Early Trials
trametinib + dabrafenib
Resistant
:
C3
BRAF G469V
Non Small Cell Lung Cancer
BRAF G469V
Non Small Cell Lung Cancer
trametinib
Resistant: C3 – Early Trials
trametinib
Resistant
:
C3
trametinib
Resistant: C3 – Early Trials
trametinib
Resistant
:
C3
BRAF G469V
Non Small Cell Lung Cancer
BRAF G469V
Non Small Cell Lung Cancer
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
BRAF G469V
Non Small Cell Lung Cancer
BRAF G469V
Non Small Cell Lung Cancer
sorafenib
Sensitive: C4 – Case Studies
sorafenib
Sensitive
:
C4
sorafenib
Sensitive: C4 – Case Studies
sorafenib
Sensitive
:
C4
BRAF G469V
Lung Adenocarcinoma
BRAF G469V
Lung Adenocarcinoma
gefitinib
Sensitive: D – Preclinical
gefitinib
Sensitive
:
D
gefitinib
Sensitive: D – Preclinical
gefitinib
Sensitive
:
D
BRAF G469V
Lung Adenocarcinoma
BRAF G469V
Lung Adenocarcinoma
osimertinib
Sensitive: D – Preclinical
osimertinib
Sensitive
:
D
osimertinib
Sensitive: D – Preclinical
osimertinib
Sensitive
:
D
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