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BIOMARKER:
BRAF mutation + TMB-L + MSI-L/dMMR
i
Other names:
BRAF, B-raf proto-oncogene, B-raf proto-oncogene, Serine/threonine kinase, V-Raf murine sarcoma viral oncogene homolog B, Serine/threonine-protein kinase B-Raf, Proto-oncogene B-Raf, BRAF1, RAFB1, B-raf proto-oncogene Serine/threonine-protein kinase, Murine sarcoma viral (V-Raf) oncogene homolog B1, B-raf serine/threonine-protein, 94 KDa B-raf protein, B-RAF1, TMB | Tumor Mutational Burden, MSI | Microsatellite instability
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Entrez ID:
673
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
CEACAM5 underexpression + MSI-H/dMMR (2)
MSI-H/dMMR + CD74 overexpression (2)
MSI-H/dMMR + HLA-B overexpression (2)
MSI-H/dMMR + HLA-DPA1 overexpression (2)
MSI-H/dMMR + HLA-DPB1 overexpression (2)
MSI-H/dMMR + HLA-DQA1 overexpression (2)
MSI-H/dMMR + HLA-DQB1 overexpression (2)
MSI-H/dMMR + HLA-DRB1 overexpression (2)
BRAF positive (1)
TMB + PD-L1 expression (0)
CEACAM5 underexpression + MSI-H/dMMR (2)
MSI-H/dMMR + CD74 overexpression (2)
MSI-H/dMMR + HLA-B overexpression (2)
MSI-H/dMMR + HLA-DPA1 overexpression (2)
MSI-H/dMMR + HLA-DPB1 overexpression (2)
MSI-H/dMMR + HLA-DQA1 overexpression (2)
MSI-H/dMMR + HLA-DQB1 overexpression (2)
MSI-H/dMMR + HLA-DRB1 overexpression (2)
BRAF positive (1)
TMB + PD-L1 expression (0)
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VERI cancer hierarchy
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BRAF mutation + TMB-L + MSI-L/dMMR
Lung Adenocarcinoma
BRAF mutation + TMB-L + MSI-L/dMMR
Lung Adenocarcinoma
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
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