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BIOMARKER:

BRCA1 mutation + BRCA2 mutation

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Entrez ID:

Related biomarkers:

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HRD + BRCA1 mutation (7)

HRD + BRCA2 mutation (7)

BRCA1 mutation + HR positive (3)

BRCA1 mutation + TMB-H (3)

BRCA2 mutation + HR positive (3)

HR positive + BRCA2 mutation (3)

BRCA1 2080delA + CCNE1 overexpression (2)

BRCA1 mutation + HER-2 negative (2)

HR negative + BRCA1 mutation (2)

HR positive + BRCA1 mutation (2)

BRCA2 mutation + HER-2 negative (2)

HR negative + BRCA2 mutation (2)

BAP1 negative + BRCA1 mutation (1)

BRCA1 hypermethylation (1)

BRCA1 mutation + AKR1C3 overexpression (1)

BRCA1 mutation + BRCA2 mutation + TMB-H (1)

BRCA1 mutation + HER-2 negative + ER positive + PGR positive (1)

BRCA1 mutation + PD-L1 expression (1)

BRCA1 mutation + RAD51B deletion (1)

BRCA1 mutation + RB1 deletion (1)

BRCA1 promoter methylation (1)

EGFR mutation + BRCA1 overexpression (1)

EGFR mutation + BRCA1 underexpression (1)

HR positive + BRCA1 mutation + PALB2 mutation (1)

PTEN deletion + BRCA1 mutation (1)

ALK rearrangement + BRCA2 F2801fs (1)

BRCA2 deletion + ATM mutation (1)

BRCA2 mutation + AKR1C3 overexpression (1)

BRCA2 mutation + ER positive (1)

BRCA2 mutation + ER positive + PGR positive (1)

BRCA2 mutation + RB1 deletion (1)

BRCA2 mutation + TMB-H (1)

BRCA2 mutation + TMB-L (1)

HR positive + BRCA2 mutation + PALB2 mutation (1)

ER positive + BRCA1 mutation (0)

ER positive + BRCA2 mutation (0)

HRD + BRCA1 mutation (7)

HRD + BRCA2 mutation (7)

BRCA1 mutation + HR positive (3)

BRCA1 mutation + TMB-H (3)

BRCA2 mutation + HR positive (3)

HR positive + BRCA2 mutation (3)

BRCA1 2080delA + CCNE1 overexpression (2)

BRCA1 mutation + HER-2 negative (2)

HR negative + BRCA1 mutation (2)

HR positive + BRCA1 mutation (2)

BRCA2 mutation + HER-2 negative (2)

HR negative + BRCA2 mutation (2)

BAP1 negative + BRCA1 mutation (1)

BRCA1 hypermethylation (1)

BRCA1 mutation + AKR1C3 overexpression (1)

BRCA1 mutation + BRCA2 mutation + TMB-H (1)

BRCA1 mutation + HER-2 negative + ER positive + PGR positive (1)

BRCA1 mutation + PD-L1 expression (1)

BRCA1 mutation + RAD51B deletion (1)

BRCA1 mutation + RB1 deletion (1)

BRCA1 promoter methylation (1)

EGFR mutation + BRCA1 overexpression (1)

EGFR mutation + BRCA1 underexpression (1)

HR positive + BRCA1 mutation + PALB2 mutation (1)

PTEN deletion + BRCA1 mutation (1)

ALK rearrangement + BRCA2 F2801fs (1)

BRCA2 deletion + ATM mutation (1)

BRCA2 mutation + AKR1C3 overexpression (1)

BRCA2 mutation + ER positive (1)

BRCA2 mutation + ER positive + PGR positive (1)

BRCA2 mutation + RB1 deletion (1)

BRCA2 mutation + TMB-H (1)

BRCA2 mutation + TMB-L (1)

HR positive + BRCA2 mutation + PALB2 mutation (1)

ER positive + BRCA1 mutation (0)

ER positive + BRCA2 mutation (0)

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BRCA1 mutation + BRCA2 mutation	Pancreatic Ductal Adenocarcinoma	BRCA1 mutation + BRCA2 mutation	Pancreatic Ductal Adenocarcinoma	Sensitive: C3 – Early Trials Sensitive : C3	Sensitive: C3 – Early Trials Sensitive : C3
BRCA1 mutation + BRCA2 mutation	Breast Cancer	BRCA1 mutation + BRCA2 mutation	Breast Cancer	fluzoparib Sensitive: C3 – Early Trials fluzoparib Sensitive : C3	fluzoparib Sensitive: C3 – Early Trials fluzoparib Sensitive : C3
BRCA1 mutation + BRCA2 mutation	Ovarian Cancer	BRCA1 mutation + BRCA2 mutation	Ovarian Cancer	fluzoparib Sensitive: C3 – Early Trials fluzoparib Sensitive : C3	fluzoparib Sensitive: C3 – Early Trials fluzoparib Sensitive : C3
BRCA1 mutation + BRCA2 mutation	Prostate Cancer	BRCA1 mutation + BRCA2 mutation	Prostate Cancer	GnRH stimulant Resistant: C3 – Early Trials GnRH stimulant Resistant : C3	GnRH stimulant Resistant: C3 – Early Trials GnRH stimulant Resistant : C3