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BIOMARKER:

CDKN2A promoter methylation

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Entrez ID:

Related biomarkers:

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ALK rearrangement + CDKN2A deletion (1)

BAP1 mutation + IDH2 R172W + CDKN2A deletion + CDKN2B deletion (1)

BRAF V600E + CDKN2A deletion + MYCN amplification (1)

BRAF V600E + CDKN2A deletion + RB1 expression (1)

BRAF V600K + CDKN2A deletion + RB1 expression (1)

CDKN2A Negative + NRAS Mutation (1)

CDKN2A deletion + CDKN2B deletion + MTAP deletion + TERT mutation (1)

CDKN2A mutation + PD-L1 overexpression (1)

CDKN2A mutation + TMB-H (1)

EGFR mutation + CCND1 expression + CDKN2A deletion (1)

NF1 mutation + CDKN2A deletion + CDKN2B deletion + MTAP deletion (1)

TMB-L + ARID1A deletion + CDKN2A deletion + CDKN2B deletion + MTAP deletion + PIK3R1 N564D + NBN P81fs*23 (1)

ALK rearrangement + CDKN2A deletion (1)

BAP1 mutation + IDH2 R172W + CDKN2A deletion + CDKN2B deletion (1)

BRAF V600E + CDKN2A deletion + MYCN amplification (1)

BRAF V600E + CDKN2A deletion + RB1 expression (1)

BRAF V600K + CDKN2A deletion + RB1 expression (1)

CDKN2A Negative + NRAS Mutation (1)

CDKN2A deletion + CDKN2B deletion + MTAP deletion + TERT mutation (1)

CDKN2A mutation + PD-L1 overexpression (1)

CDKN2A mutation + TMB-H (1)

EGFR mutation + CCND1 expression + CDKN2A deletion (1)

NF1 mutation + CDKN2A deletion + CDKN2B deletion + MTAP deletion (1)

TMB-L + ARID1A deletion + CDKN2A deletion + CDKN2B deletion + MTAP deletion + PIK3R1 N564D + NBN P81fs*23 (1)

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CDKN2A promoter methylation	Melanoma	CDKN2A promoter methylation	Melanoma	palbociclib Sensitive: D – Preclinical palbociclib Sensitive : D	palbociclib Sensitive: D – Preclinical palbociclib Sensitive : D
CDKN2A promoter methylation	Gastric Cancer	CDKN2A promoter methylation	Gastric Cancer	abemaciclib Sensitive: D – Preclinical abemaciclib Sensitive : D	abemaciclib Sensitive: D – Preclinical abemaciclib Sensitive : D