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BIOMARKER:
EGFR C797S + KRAS amplification + RB1 deletion
i
Other names:
EGFR, ERBB, ERBB1, Epidermal growth factor receptor, RB1, RB Transcriptional Corepressor 1, Protein Phosphatase 1 Regulatory Subunit 130, Prepro-Retinoblastoma-Associated Protein, Retinoblastoma-Associated Protein, Retinoblastoma 1, P110-RB1, P105-Rb, Pp110, PRb, Exon 17 Tumor GOS561 Substitution Mutation Causes Premature Stop, GOS563 Exon 17 Substitution Mutation Causes Premature Stop, Retinoblastoma Suspectibility Protein, Osteosarcoma, PPP1R130, OSRC, RB, Rb, pRb
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Entrez ID:
1956
;
3845
;
5925
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
EGFR expression (46)
EGFR overexpression (34)
EGFR positive (8)
RB1 expression (7)
EGFR negative (6)
EGFR negative + ALK negative (4)
EGFR expression + ALK positive (3)
EGFRVIII expression + PTEN expression (3)
EGFRvIII expression (3)
EGFR expression + MET expression (2)
EGFR overexpression + HER-2 overexpression (2)
MMP17 expression + EGFR expression + RB1 expression (2)
MUC1 expression + EGFR expression (2)
TROP2 expression + EGFR expression (2)
KRAS overexpression (2)
RB1 overexpression (2)
RB1 positive (2)
EGFR expression + HER-2 expression (1)
EGFR underexpression (1)
EGFRVIII overexpression (1)
EPHA2 overexpression + EGFR overexpression (1)
GPC3 positive + EGFR expression (1)
KRAS G13D overexpression (1)
RB1 negative (1)
DRD2 expression + EGFR overexpression (0)
YAP1 overexpression + EGFR overexpression (0)
KRAS expression (0)
EGFR expression (46)
EGFR overexpression (34)
EGFR positive (8)
RB1 expression (7)
EGFR negative (6)
EGFR negative + ALK negative (4)
EGFR expression + ALK positive (3)
EGFRVIII expression + PTEN expression (3)
EGFRvIII expression (3)
EGFR expression + MET expression (2)
EGFR overexpression + HER-2 overexpression (2)
MMP17 expression + EGFR expression + RB1 expression (2)
MUC1 expression + EGFR expression (2)
TROP2 expression + EGFR expression (2)
KRAS overexpression (2)
RB1 overexpression (2)
RB1 positive (2)
EGFR expression + HER-2 expression (1)
EGFR underexpression (1)
EGFRVIII overexpression (1)
EPHA2 overexpression + EGFR overexpression (1)
GPC3 positive + EGFR expression (1)
KRAS G13D overexpression (1)
RB1 negative (1)
DRD2 expression + EGFR overexpression (0)
YAP1 overexpression + EGFR overexpression (0)
KRAS expression (0)
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Trials
VERI cancer hierarchy
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EGFR C797S + KRAS amplification + RB1 deletion
Non Small Cell Lung Cancer
EGFR C797S + KRAS amplification + RB1 deletion
Non Small Cell Lung Cancer
amivantamab-vmjw
Sensitive: D – Preclinical
amivantamab-vmjw
Sensitive
:
D
amivantamab-vmjw
Sensitive: D – Preclinical
amivantamab-vmjw
Sensitive
:
D
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