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BIOMARKER:
EGFR exon 19 deletion + NRAS Q61K
i
Other names:
NRAS1, N-Ras Protein Part 4, Neuroblastoma RAS Viral (V-Ras) Oncogene Homolog, NRAS, Neuroblastoma RAS Viral Oncogene Homolog, NRAS Proto-Oncogene, EGFR, ERBB, ERBB1, Epidermal growth factor receptor
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Entrez ID:
1956
;
4893
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
EGFR expression (46)
EGFR overexpression (34)
EGFR positive (8)
EGFR negative (6)
EGFR negative + ALK negative (4)
NRAS overexpression (4)
EGFR expression + ALK positive (3)
EGFRVIII expression + PTEN expression (3)
EGFRvIII expression (3)
EGFR expression + MET expression (2)
EGFR overexpression + HER-2 overexpression (2)
MMP17 expression + EGFR expression + RB1 expression (2)
MUC1 expression + EGFR expression (2)
TROP2 expression + EGFR expression (2)
EGFR expression + HER-2 expression (1)
EGFR underexpression (1)
EGFRVIII overexpression (1)
EPHA2 overexpression + EGFR overexpression (1)
GPC3 positive + EGFR expression (1)
NRAS expression (1)
DRD2 expression + EGFR overexpression (0)
YAP1 overexpression + EGFR overexpression (0)
EGFR expression (46)
EGFR overexpression (34)
EGFR positive (8)
EGFR negative (6)
EGFR negative + ALK negative (4)
NRAS overexpression (4)
EGFR expression + ALK positive (3)
EGFRVIII expression + PTEN expression (3)
EGFRvIII expression (3)
EGFR expression + MET expression (2)
EGFR overexpression + HER-2 overexpression (2)
MMP17 expression + EGFR expression + RB1 expression (2)
MUC1 expression + EGFR expression (2)
TROP2 expression + EGFR expression (2)
EGFR expression + HER-2 expression (1)
EGFR underexpression (1)
EGFRVIII overexpression (1)
EPHA2 overexpression + EGFR overexpression (1)
GPC3 positive + EGFR expression (1)
NRAS expression (1)
DRD2 expression + EGFR overexpression (0)
YAP1 overexpression + EGFR overexpression (0)
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EGFR exon 19 deletion + NRAS Q61K
Lung Adenocarcinoma
EGFR exon 19 deletion + NRAS Q61K
Lung Adenocarcinoma
gefitinib
Resistant: D – Preclinical
gefitinib
Resistant
:
D
gefitinib
Resistant: D – Preclinical
gefitinib
Resistant
:
D
EGFR exon 19 deletion + NRAS Q61K
Lung Adenocarcinoma
EGFR exon 19 deletion + NRAS Q61K
Lung Adenocarcinoma
gefitinib + selumetinib
Sensitive: D – Preclinical
gefitinib + selumetinib
Sensitive
:
D
gefitinib + selumetinib
Sensitive: D – Preclinical
gefitinib + selumetinib
Sensitive
:
D
EGFR exon 19 deletion + NRAS Q61K
Lung Adenocarcinoma
EGFR exon 19 deletion + NRAS Q61K
Lung Adenocarcinoma
gefitinib + CI-1040
Sensitive: D – Preclinical
gefitinib + CI-1040
Sensitive
:
D
gefitinib + CI-1040
Sensitive: D – Preclinical
gefitinib + CI-1040
Sensitive
:
D
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