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BIOMARKER:
EGFR L858R
i
Other names:
EGFR, ERBB, ERBB1, Epidermal growth factor receptor
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Entrez ID:
1956
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
EGFR expression (46)
EGFR overexpression (34)
EGFR positive (8)
EGFR negative (6)
EGFR negative + ALK negative (4)
EGFR expression + ALK positive (3)
EGFRVIII expression + PTEN expression (3)
EGFRvIII expression (3)
EGFR expression + MET expression (2)
EGFR overexpression + HER-2 overexpression (2)
MMP17 expression + EGFR expression + RB1 expression (2)
MUC1 expression + EGFR expression (2)
TROP2 expression + EGFR expression (2)
EGFR expression + HER-2 expression (1)
EGFR underexpression (1)
EGFRVIII overexpression (1)
EPHA2 overexpression + EGFR overexpression (1)
GPC3 positive + EGFR expression (1)
DRD2 expression + EGFR overexpression (0)
YAP1 overexpression + EGFR overexpression (0)
EGFR expression (46)
EGFR overexpression (34)
EGFR positive (8)
EGFR negative (6)
EGFR negative + ALK negative (4)
EGFR expression + ALK positive (3)
EGFRVIII expression + PTEN expression (3)
EGFRvIII expression (3)
EGFR expression + MET expression (2)
EGFR overexpression + HER-2 overexpression (2)
MMP17 expression + EGFR expression + RB1 expression (2)
MUC1 expression + EGFR expression (2)
TROP2 expression + EGFR expression (2)
EGFR expression + HER-2 expression (1)
EGFR underexpression (1)
EGFRVIII overexpression (1)
EPHA2 overexpression + EGFR overexpression (1)
GPC3 positive + EGFR expression (1)
DRD2 expression + EGFR overexpression (0)
YAP1 overexpression + EGFR overexpression (0)
›
Related tests:
FoundationOne® CDx (110)
Guardant360® CDx (54)
FoundationOne® Liquid CDx (21)
cobas® EGFR Mutation Test v2 (13)
therascreen® EGFR RGQ PCR Kit (5)
MI Cancer Seek™
OncoReveal™ Dx Lung and Colon Cancer Assay (O/RDx-LCCA)
Target Selector™ EGFR Mutation Assay
FoundationOne® CDx (110)
Guardant360® CDx (54)
FoundationOne® Liquid CDx (21)
cobas® EGFR Mutation Test v2 (13)
therascreen® EGFR RGQ PCR Kit (5)
MI Cancer Seek™
OncoReveal™ Dx Lung and Colon Cancer Assay (O/RDx-LCCA)
Target Selector™ EGFR Mutation Assay
Associations
News
Trials
VERI cancer hierarchy
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EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
afatinib
Sensitive: A1 - Approval
afatinib
Sensitive
:
A1
afatinib
Sensitive: A1 - Approval
afatinib
Sensitive
:
A1
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
osimertinib
Sensitive: A1 - Approval
osimertinib
Sensitive
:
A1
osimertinib
Sensitive: A1 - Approval
osimertinib
Sensitive
:
A1
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
dacomitinib
Sensitive: A1 - Approval
dacomitinib
Sensitive
:
A1
dacomitinib
Sensitive: A1 - Approval
dacomitinib
Sensitive
:
A1
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
gefitinib
Sensitive: A1 - Approval
gefitinib
Sensitive
:
A1
gefitinib
Sensitive: A1 - Approval
gefitinib
Sensitive
:
A1
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
erlotinib
Sensitive: A1 - Approval
erlotinib
Sensitive
:
A1
erlotinib
Sensitive: A1 - Approval
erlotinib
Sensitive
:
A1
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
erlotinib + ramucirumab
Sensitive: A1 - Approval
erlotinib + ramucirumab
Sensitive
:
A1
erlotinib + ramucirumab
Sensitive: A1 - Approval
erlotinib + ramucirumab
Sensitive
:
A1
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
amivantamab-vmjw + lazertinib
Sensitive: A1 - Approval
amivantamab-vmjw + lazertinib
Sensitive
:
A1
amivantamab-vmjw + lazertinib
Sensitive: A1 - Approval
amivantamab-vmjw + lazertinib
Sensitive
:
A1
EGFR L858R
Lung Non-Squamous Non-Small Cell Cancer
EGFR L858R
Lung Non-Squamous Non-Small Cell Cancer
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
bevacizumab + erlotinib
Sensitive: A2 - Guideline
bevacizumab + erlotinib
Sensitive
:
A2
bevacizumab + erlotinib
Sensitive: A2 - Guideline
bevacizumab + erlotinib
Sensitive
:
A2
EGFR L858R
Lung Non-Squamous Non-Small Cell Cancer
EGFR L858R
Lung Non-Squamous Non-Small Cell Cancer
osimertinib
Sensitive: A2 - Guideline
osimertinib
Sensitive
:
A2
osimertinib
Sensitive: A2 - Guideline
osimertinib
Sensitive
:
A2
EGFR L858R
Lung Non-Squamous Non-Small Cell Cancer
EGFR L858R
Lung Non-Squamous Non-Small Cell Cancer
gefitinib
Sensitive: A2 - Guideline
gefitinib
Sensitive
:
A2
gefitinib
Sensitive: A2 - Guideline
gefitinib
Sensitive
:
A2
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