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DRUG:

camibirstat (FHD-286)

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Company:

Foghorn Therap

Drug class:

SMARCA2 inhibitor, SMARCA4 inhibitor

Related drugs:

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MLL rearrangement + FLT3 mutation	Acute Myelogenous Leukemia	MLL rearrangement + FLT3 mutation	Acute Myelogenous Leukemia	FHD-286 Sensitive: D – Preclinical FHD-286 Sensitive : D	FHD-286 Sensitive: D – Preclinical FHD-286 Sensitive : D
FLT3-ITD mutation + NPM1 mutation	Acute Myelogenous Leukemia	FLT3-ITD mutation + NPM1 mutation	Acute Myelogenous Leukemia	revumenib + FHD-286 Sensitive: D – Preclinical revumenib + FHD-286 Sensitive : D	revumenib + FHD-286 Sensitive: D – Preclinical revumenib + FHD-286 Sensitive : D
FLT3-ITD mutation + NPM1 mutation	Acute Myelogenous Leukemia	FLT3-ITD mutation + NPM1 mutation	Acute Myelogenous Leukemia	OTX015 + FHD-286 Sensitive: D – Preclinical OTX015 + FHD-286 Sensitive : D	OTX015 + FHD-286 Sensitive: D – Preclinical OTX015 + FHD-286 Sensitive : D