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BIOMARKER:
IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK1 fusion
i
Other names:
HEL-216, HEL-S-26, Epididymis Luminal Protein 216, Isocitrate Dehydrogenase 1 (NADP+), Epididymis Secretory Protein Li 26, IDH1, Isocitrate Dehydrogenase (NADP(+)) 1, Isocitrate Dehydrogenase 1 (NADP+), Soluble, NTRK1, MTC, TRK, TRKA, Neurotrophic tyrosine kinase, receptor, type 1
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Entrez ID:
3417
;
4914
Related biomarkers:
Expression
Mutation
Fusion
Others
‹
IDH1 mutation (79)
IDH1 R132H (9)
IDH1 R132C (5)
IDH wild-type (3)
IDH1 R132 (3)
NTRK1 mutation (3)
FLT3-ITD mutation + IDH1 mutation (2)
IDH1 R132G (2)
IDH1 wild-type + BRAF mutation (2)
IDH1 wild-type + NF1 mutation (2)
DNMT3A mutation + IDH mutation (1)
EGFR L858R + IDH1 R132C (1)
EGFR mutation + IDH1 mutation (1)
EGFR mutation+ IDH1 R132H (1)
FLT3 mutation + IDH1 mutation (1)
IDH1 R132C + EGFR L861Q (1)
IDH1 R132C + IDH1 S280F (1)
IDH1 R132C + PIK3CA E545K + IDH2 R172K (1)
IDH1 R132H + PTEN C78T (1)
IDH1 R132L (1)
IDH1 R132S (1)
IDH1 R132V (1)
IDH1 mutation + TP53 mutation (1)
IDH1 rs1437410 (1)
LMNA-NTRK1 rearrangement (1)
NTRK1 F589L + NTRK1 G595R (1)
NTRK1 G595R (1)
NTRK1 G667C (1)
IDH mutation + BRAF V600E (0)
IDH mutation + Chr del(1p) + Chr del(19q) (0)
IDH mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (0)
IDH mutation + Chr del(1p) + Chr del(19q) + NTRK fusion (0)
IDH mutation + NTRK fusion (0)
NTRK1 translocation (0)
IDH1 mutation (79)
IDH1 R132H (9)
IDH1 R132C (5)
IDH wild-type (3)
IDH1 R132 (3)
NTRK1 mutation (3)
FLT3-ITD mutation + IDH1 mutation (2)
IDH1 R132G (2)
IDH1 wild-type + BRAF mutation (2)
IDH1 wild-type + NF1 mutation (2)
DNMT3A mutation + IDH mutation (1)
EGFR L858R + IDH1 R132C (1)
EGFR mutation + IDH1 mutation (1)
EGFR mutation+ IDH1 R132H (1)
FLT3 mutation + IDH1 mutation (1)
IDH1 R132C + EGFR L861Q (1)
IDH1 R132C + IDH1 S280F (1)
IDH1 R132C + PIK3CA E545K + IDH2 R172K (1)
IDH1 R132H + PTEN C78T (1)
IDH1 R132L (1)
IDH1 R132S (1)
IDH1 R132V (1)
IDH1 mutation + TP53 mutation (1)
IDH1 rs1437410 (1)
LMNA-NTRK1 rearrangement (1)
NTRK1 F589L + NTRK1 G595R (1)
NTRK1 G595R (1)
NTRK1 G667C (1)
IDH mutation + BRAF V600E (0)
IDH mutation + Chr del(1p) + Chr del(19q) (0)
IDH mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (0)
IDH mutation + Chr del(1p) + Chr del(19q) + NTRK fusion (0)
IDH mutation + NTRK fusion (0)
NTRK1 translocation (0)
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IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK1 fusion
Oligodendroglioma
IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK1 fusion
Oligodendroglioma
entrectinib
Sensitive: A2 - Guideline
entrectinib
Sensitive
:
A2
entrectinib
Sensitive: A2 - Guideline
entrectinib
Sensitive
:
A2
IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK1 fusion
Oligodendroglioma
IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK1 fusion
Oligodendroglioma
larotrectinib
Sensitive: A2 - Guideline
larotrectinib
Sensitive
:
A2
larotrectinib
Sensitive: A2 - Guideline
larotrectinib
Sensitive
:
A2
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