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BIOMARKER:
IDH1 mutation + NTRK1 fusion
i
Other names:
NTRK1, MTC, TRK, TRKA, Neurotrophic tyrosine kinase, receptor, type 1, HEL-216, HEL-S-26, Epididymis Luminal Protein 216, Isocitrate Dehydrogenase 1 (NADP+), Epididymis Secretory Protein Li 26, IDH1, Isocitrate Dehydrogenase (NADP(+)) 1, Isocitrate Dehydrogenase 1 (NADP+), Soluble
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Entrez ID:
3417
;
4914
Related biomarkers:
Expression
Mutation
Fusion
Others
‹
IDH1 mutation + Chr del(1p) + Chr del(19q) (10)
IDH1 mutation + BRAF V600E (2)
IDH1 mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (2)
IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK1 fusion (2)
IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK2 fusion (2)
IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK3 fusion (2)
IDH1 mutation + NTRK2 fusion (2)
IDH1 mutation + NTRK3 fusion (2)
MYC overexpression + IDH1 mutation (2)
EML4-ALK + ALK G1202R + LIPI-NTRK1 (2)
IDH2 mutation + Chr del(1p) + Chr del(19q) + NTRK1 fusion (2)
IDH2 mutation + NTRK1 fusion (2)
NCOR2-NTRK1 fusion + TMB-H (2)
IDH wild-type + FGFR3 S249C + TP53 V73fs (1)
IDH1 R132S + H3K27me3 loss + MET exon 14 skipping mutation (1)
IDH1 mutation + ATRX deletion + TP53 deletion (1)
IDH1 mutation + FGFR2 fusion (1)
IDH1 mutation + FGFR2 rearrangement (1)
IDH1 mutation + MGMT promoter methylation (1)
IDH1 mutation + MYC amplification + MAPRE1 overexpression (1)
IDH1 mutation + TMB-L (1)
IDH1 mutation + WT1 overexpression (1)
EGFR exon 19 deletion + LMNA-NTRK1 fusion + EGFR T790M (1)
LMNA-NTRK1 fusion + NTRK1 G595R (1)
MSI-H/dMMR + NTRK1 fusion (1)
NOTCH2-NTRK1 fusion + EGFR L858R (1)
SQSTM1-NTRK1 + PIK3CA E545K + TP53 L145R + PD-L1 overexpression (1)
TPM3-NTRK1 fusion + ALK L1196M (1)
IDH1 mutation + Chr del(1p) + Chr del(19q) + MGMT promoter methylation (0)
IDH1 mutation + Chr del(1p) + Chr del(19q) (10)
IDH1 mutation + BRAF V600E (2)
IDH1 mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (2)
IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK1 fusion (2)
IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK2 fusion (2)
IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK3 fusion (2)
IDH1 mutation + NTRK2 fusion (2)
IDH1 mutation + NTRK3 fusion (2)
MYC overexpression + IDH1 mutation (2)
EML4-ALK + ALK G1202R + LIPI-NTRK1 (2)
IDH2 mutation + Chr del(1p) + Chr del(19q) + NTRK1 fusion (2)
IDH2 mutation + NTRK1 fusion (2)
NCOR2-NTRK1 fusion + TMB-H (2)
IDH wild-type + FGFR3 S249C + TP53 V73fs (1)
IDH1 R132S + H3K27me3 loss + MET exon 14 skipping mutation (1)
IDH1 mutation + ATRX deletion + TP53 deletion (1)
IDH1 mutation + FGFR2 fusion (1)
IDH1 mutation + FGFR2 rearrangement (1)
IDH1 mutation + MGMT promoter methylation (1)
IDH1 mutation + MYC amplification + MAPRE1 overexpression (1)
IDH1 mutation + TMB-L (1)
IDH1 mutation + WT1 overexpression (1)
EGFR exon 19 deletion + LMNA-NTRK1 fusion + EGFR T790M (1)
LMNA-NTRK1 fusion + NTRK1 G595R (1)
MSI-H/dMMR + NTRK1 fusion (1)
NOTCH2-NTRK1 fusion + EGFR L858R (1)
SQSTM1-NTRK1 + PIK3CA E545K + TP53 L145R + PD-L1 overexpression (1)
TPM3-NTRK1 fusion + ALK L1196M (1)
IDH1 mutation + Chr del(1p) + Chr del(19q) + MGMT promoter methylation (0)
›
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IDH1 mutation + NTRK1 fusion
Astrocytoma
IDH1 mutation + NTRK1 fusion
Astrocytoma
entrectinib
Sensitive: A2 - Guideline
entrectinib
Sensitive
:
A2
entrectinib
Sensitive: A2 - Guideline
entrectinib
Sensitive
:
A2
IDH1 mutation + NTRK1 fusion
Astrocytoma
IDH1 mutation + NTRK1 fusion
Astrocytoma
larotrectinib
Sensitive: A2 - Guideline
larotrectinib
Sensitive
:
A2
larotrectinib
Sensitive: A2 - Guideline
larotrectinib
Sensitive
:
A2
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