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BIOMARKER:
IDH2 mutation + NTRK1 fusion
i
Other names:
IDH2, Isocitrate Dehydrogenase (NADP(+)) 2, Isocitrate Dehydrogenase (NADP(+)) 2, Mitochondrial, Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial, Isocitrate Dehydrogenase [NADP], Mitochondrial, Oxalosuccinate Decarboxylase, NADP(+)-Specific ICDH, ICD-M, IDH, IDP, MNADP-IDH, D2HGA2, IDHM, IDPM, NTRK1, MTC, TRK, TRKA, Neurotrophic tyrosine kinase, receptor, type 1
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Entrez ID:
4914
;
3418
Related biomarkers:
Expression
Mutation
Fusion
Others
‹
IDH2 mutation (70)
IDH2 R172K (8)
NTRK1 mutation (3)
IDH wild-type (3)
FLT3-ITD mutation + IDH2 mutation (2)
IDH2 R140Q (2)
LMNA-NTRK1 rearrangement (1)
NTRK1 F589L + NTRK1 G595R (1)
NTRK1 G595R (1)
NTRK1 G667C (1)
DNMT3A mutation + IDH mutation (1)
IDH1 R132C + PIK3CA E545K + IDH2 R172K (1)
IDH2 R140 (1)
IDH2 R140Q + NPM1 mutation (1)
IDH2 R140W + EGFR L858R (1)
IDH2 R172 (1)
IDH2 R172G (1)
IDH2 mutation + NRAS mutation (1)
IDH2 mutation + SRSF2 mutation (1)
IDH2 mutation + TP53 mutation (1)
IDH2 mutation + NPM1 mutation (1)
PIK3CA mutation + TTN mutation + IDH2 mutation (1)
TTN mutation + IDH2 mutation (1)
NTRK1 translocation (0)
IDH mutation + BRAF V600E (0)
IDH mutation + Chr del(1p) + Chr del(19q) (0)
IDH mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (0)
IDH mutation + Chr del(1p) + Chr del(19q) + NTRK fusion (0)
IDH mutation + NTRK fusion (0)
IDH2 mutation (70)
IDH2 R172K (8)
NTRK1 mutation (3)
IDH wild-type (3)
FLT3-ITD mutation + IDH2 mutation (2)
IDH2 R140Q (2)
LMNA-NTRK1 rearrangement (1)
NTRK1 F589L + NTRK1 G595R (1)
NTRK1 G595R (1)
NTRK1 G667C (1)
DNMT3A mutation + IDH mutation (1)
IDH1 R132C + PIK3CA E545K + IDH2 R172K (1)
IDH2 R140 (1)
IDH2 R140Q + NPM1 mutation (1)
IDH2 R140W + EGFR L858R (1)
IDH2 R172 (1)
IDH2 R172G (1)
IDH2 mutation + NRAS mutation (1)
IDH2 mutation + SRSF2 mutation (1)
IDH2 mutation + TP53 mutation (1)
IDH2 mutation + NPM1 mutation (1)
PIK3CA mutation + TTN mutation + IDH2 mutation (1)
TTN mutation + IDH2 mutation (1)
NTRK1 translocation (0)
IDH mutation + BRAF V600E (0)
IDH mutation + Chr del(1p) + Chr del(19q) (0)
IDH mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (0)
IDH mutation + Chr del(1p) + Chr del(19q) + NTRK fusion (0)
IDH mutation + NTRK fusion (0)
›
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IDH2 mutation + NTRK1 fusion
Astrocytoma
IDH2 mutation + NTRK1 fusion
Astrocytoma
entrectinib
Sensitive: A2 - Guideline
entrectinib
Sensitive
:
A2
entrectinib
Sensitive: A2 - Guideline
entrectinib
Sensitive
:
A2
IDH2 mutation + NTRK1 fusion
Astrocytoma
IDH2 mutation + NTRK1 fusion
Astrocytoma
larotrectinib
Sensitive: A2 - Guideline
larotrectinib
Sensitive
:
A2
larotrectinib
Sensitive: A2 - Guideline
larotrectinib
Sensitive
:
A2
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