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BIOMARKER:
KDR Q472H + KIT M541L
i
Other names:
KIT, KIT proto-oncogene receptor tyrosine kinase, C-Kit, CD117, PBT, SCFR, Stem Cell Factor Receptor, V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, KDR, CD309, FLK1, VEGFR, VEGFR2, Kinase insert domain receptor (a type III receptor tyrosine kinase)
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Entrez ID:
3815
;
3791
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
Chr t(8;21) + KIT mutation (4)
Chr t(8;21)(q22;q22) + RUNX1-RUNX1T1 fusion + KIT exon 17 mutation + CSF3R mutation (4)
Chr t(8;21)(q22;q22) + RUNX1-RUNX1T1 fusion + KIT exon 17 mutation (3)
KIT P577del + KIT W557Lfs*5 + KIT Y823D (2)
KDR elevation (2)
Chr inv(16)t(16;16) + KIT mutation (1)
KIT wild-type + SDHB deletion (1)
RUNX1-RUNX1T1 fusion + KIT D816 (1)
EGFR L858R + KDR overexpression + VEGFC overexpression (1)
KDR amplification + FLT4 amplification + MCL1 amplification + TP53 R213 + TP53 H179Y + ARID1A Q2128 (1)
MSI-H/dMMR + KDR overexpression (1)
Chr t(8;21) + KIT mutation (4)
Chr t(8;21)(q22;q22) + RUNX1-RUNX1T1 fusion + KIT exon 17 mutation + CSF3R mutation (4)
Chr t(8;21)(q22;q22) + RUNX1-RUNX1T1 fusion + KIT exon 17 mutation (3)
KIT P577del + KIT W557Lfs*5 + KIT Y823D (2)
KDR elevation (2)
Chr inv(16)t(16;16) + KIT mutation (1)
KIT wild-type + SDHB deletion (1)
RUNX1-RUNX1T1 fusion + KIT D816 (1)
EGFR L858R + KDR overexpression + VEGFC overexpression (1)
KDR amplification + FLT4 amplification + MCL1 amplification + TP53 R213 + TP53 H179Y + ARID1A Q2128 (1)
MSI-H/dMMR + KDR overexpression (1)
›
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KDR Q472H + KIT M541L
Sarcoma
KDR Q472H + KIT M541L
Sarcoma
vandetanib
Sensitive: C4 – Case Studies
vandetanib
Sensitive
:
C4
vandetanib
Sensitive: C4 – Case Studies
vandetanib
Sensitive
:
C4
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