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DRUG:

lucitanib (E 3810)

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Company:

Clovis, HaiHe Biopharma, Servier

Drug class:

FGFR inhibitor, VEGFR inhibitor, PDGFR α-β inhibitor

Related drugs:

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FGFR1 overexpression + HR positive	HER2 Negative Breast Cancer	FGFR1 overexpression + HR positive	HER2 Negative Breast Cancer	E 3810 Sensitive: C3 – Early Trials E 3810 Sensitive : C3	E 3810 Sensitive: C3 – Early Trials E 3810 Sensitive : C3
FGF amplification	Breast Cancer	FGF amplification	Breast Cancer	E 3810 Sensitive: C3 – Early Trials E 3810 Sensitive : C3	E 3810 Sensitive: C3 – Early Trials E 3810 Sensitive : C3
FGFR1 amplification + HR positive	HER2 Negative Breast Cancer	FGFR1 amplification + HR positive	HER2 Negative Breast Cancer	E 3810 Sensitive: C3 – Early Trials E 3810 Sensitive : C3	E 3810 Sensitive: C3 – Early Trials E 3810 Sensitive : C3
PALB2 mutation	Endometrial Cancer	PALB2 mutation	Endometrial Cancer	rucaparib + E 3810 Sensitive: C4 – Case Studies rucaparib + E 3810 Sensitive : C4	rucaparib + E 3810 Sensitive: C4 – Case Studies rucaparib + E 3810 Sensitive : C4