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BIOMARKER:
MSH2 deletion + MSH6 deletion
i
Other names:
MSH6, GTBP, MutS homolog 6, MSH2, MutS Homolog 2, HMSH2, MutS (E. Coli) Homolog 2, MutS Homolog 2, Nonpolyposis Type 1, DNA Mismatch Repair Protein Msh2, MutS Protein Homolog 2, HNPCC1, HNPCC, LCFS2, COCA1, FCC1
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Entrez ID:
2956
;
4436
Related biomarkers:
Expression
Mutation
CNA
Others
‹
MSH2 negative + MSH6 negative (1)
MSH6 expression (0)
MSH2 negative + MSH6 negative (1)
MSH6 expression (0)
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VERI cancer hierarchy
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MSH2 deletion + MSH6 deletion
Endometrial Cancer
MSH2 deletion + MSH6 deletion
Endometrial Cancer
dostarlimab-gxly
Sensitive: C3 – Early Trials
dostarlimab-gxly
Sensitive
:
C3
dostarlimab-gxly
Sensitive: C3 – Early Trials
dostarlimab-gxly
Sensitive
:
C3
MSH2 deletion + MSH6 deletion
Rectal Cancer
MSH2 deletion + MSH6 deletion
Rectal Cancer
nivolumab + ipilimumab
Sensitive: C3 – Early Trials
nivolumab + ipilimumab
Sensitive
:
C3
nivolumab + ipilimumab
Sensitive: C3 – Early Trials
nivolumab + ipilimumab
Sensitive
:
C3
MSH2 deletion + MSH6 deletion
Pituitary Gland Carcinoma
MSH2 deletion + MSH6 deletion
Pituitary Gland Carcinoma
temozolomide
Resistant: C4 – Case Studies
temozolomide
Resistant
:
C4
temozolomide
Resistant: C4 – Case Studies
temozolomide
Resistant
:
C4
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