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BIOMARKER:
MSI-H/dMMR + POLE P286R
i
Other names:
MSI-H, Microsatellite instability - high, dMMR, POLE1, DNA Polymerase Epsilon Catalytic Subunit, DNA Polymerase Epsilon Catalytic Subunit A, Polymerase (DNA) Epsilon Catalytic Subunit, DNA Polymerase II Subunit A, Polymerase (DNA Directed) Epsilon Catalytic Subunit, DNA Polymerase Epsilon Catalytic Subunit Protein, Polymerase (DNA Directed) Epsilon
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Entrez ID:
5426
Related biomarkers:
Mutation
Others
‹
MSI-H/dMMR + POLE mutation (4)
MSI-H/dMMR + TMB-H + POLE mutation (1)
POLE E790Q + ERBB2 amplification + TMB-H (1)
POLE P286R + TMB-H (1)
POLE V1368M + ERBB3 G1271S + TNFAIP3 P714A + PRKN I69T + TSC2 G1399R + TMB-L (1)
POLE mutation + PD-L1 negative + TMB-H (1)
MSI-H/dMMR + POLE mutation (4)
MSI-H/dMMR + TMB-H + POLE mutation (1)
POLE E790Q + ERBB2 amplification + TMB-H (1)
POLE P286R + TMB-H (1)
POLE V1368M + ERBB3 G1271S + TNFAIP3 P714A + PRKN I69T + TSC2 G1399R + TMB-L (1)
POLE mutation + PD-L1 negative + TMB-H (1)
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VERI cancer hierarchy
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MSI-H/dMMR + POLE P286R
Colon Cancer
MSI-H/dMMR + POLE P286R
Colon Cancer
sintilimab
Sensitive: C4 – Case Studies
sintilimab
Sensitive
:
C4
sintilimab
Sensitive: C4 – Case Studies
sintilimab
Sensitive
:
C4
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