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BIOMARKER:
NFE2L2 mutation
i
Other names:
NFE2L2, Nuclear Factor Erythroid 2 Like 2, Nuclear Factor Erythroid 2-Related Factor 2, NF-E2-Related Factor 2, HEBP1, Nrf-2, NRF2, Nuclear Factor Erythroid Derived 2 Like 2, Nuclear Factor (Erythroid-Derived 2)-Like 2, Nuclear Factor Erythroid-Derived 2-Like 2, Nuclear Factor Erythroid 2-Like 2, NFE2-Related Factor 2, IMDDHH
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Entrez ID:
4780
Related biomarkers:
Expression
Mutation
‹
NFE2L2 E79K (1)
NFE2L2 mutation + CTNNB1 mutation (1)
NFE2L2 mutation + STK11 mutation (1)
KEAP1 mutation + NFE2L2 mutation + STK11 mutation (0)
NFE2L2 E79K (1)
NFE2L2 mutation + CTNNB1 mutation (1)
NFE2L2 mutation + STK11 mutation (1)
KEAP1 mutation + NFE2L2 mutation + STK11 mutation (0)
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NFE2L2 mutation
Non Small Cell Lung Cancer
NFE2L2 mutation
Non Small Cell Lung Cancer
DRP-104
Sensitive: B - Late Trials
DRP-104
Sensitive
:
B
DRP-104
Sensitive: B - Late Trials
DRP-104
Sensitive
:
B
NFE2L2 mutation
Lung Non-Small Cell Squamous Cancer
NFE2L2 mutation
Lung Non-Small Cell Squamous Cancer
CB-228
Sensitive: B - Late Trials
CB-228
Sensitive
:
B
CB-228
Sensitive: B - Late Trials
CB-228
Sensitive
:
B
NFE2L2 mutation
Solid Tumor
NFE2L2 mutation
Solid Tumor
IPN60090
Sensitive: C2 – Inclusion Criteria
IPN60090
Sensitive
:
C2
IPN60090
Sensitive: C2 – Inclusion Criteria
IPN60090
Sensitive
:
C2
NFE2L2 mutation
Lung Cancer
NFE2L2 mutation
Lung Cancer
IPN60090
Sensitive: C2 – Inclusion Criteria
IPN60090
Sensitive
:
C2
IPN60090
Sensitive: C2 – Inclusion Criteria
IPN60090
Sensitive
:
C2
NFE2L2 mutation
Lung Cancer
NFE2L2 mutation
Lung Cancer
CB-228
Sensitive: C2 – Inclusion Criteria
CB-228
Sensitive
:
C2
CB-228
Sensitive: C2 – Inclusion Criteria
CB-228
Sensitive
:
C2
NFE2L2 mutation
Non Small Cell Lung Cancer
NFE2L2 mutation
Non Small Cell Lung Cancer
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
NFE2L2 mutation
Lung Non-Small Cell Squamous Cancer
NFE2L2 mutation
Lung Non-Small Cell Squamous Cancer
CB-228 + CB-839
Sensitive: C3 – Early Trials
CB-228 + CB-839
Sensitive
:
C3
CB-228 + CB-839
Sensitive: C3 – Early Trials
CB-228 + CB-839
Sensitive
:
C3
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