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BIOMARKER:
NRAS Q61H
i
Other names:
NRAS1, HRAS1, N-Ras Protein Part 4, Neuroblastoma RAS Viral (V-Ras) Oncogene Homolog, NRAS, Neuroblastoma RAS Viral Oncogene Homolog, NRAS Proto-Oncogene, GTPase
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Entrez ID:
4893
Related biomarkers:
Expression
Mutation
CNA
Others
‹
EGFR exon 19 deletion + NRAS Q61K (3)
PD-L1 expression + NRAS Q61R + BRAF D594N (2)
CDKN2A Negative + NRAS Mutation (1)
Chr t(11;14) + NRAS mutation (1)
KRAS wild-type + NRAS wild-type + MSI-H/dMMR (1)
MLL-AFF1 fusion + NRAS mutation (1)
NRAS mutation + BRAF wild-type (1)
NRAS wild-type + NOTCH4 mutation (1)
EGFR exon 19 deletion + NRAS Q61K (3)
PD-L1 expression + NRAS Q61R + BRAF D594N (2)
CDKN2A Negative + NRAS Mutation (1)
Chr t(11;14) + NRAS mutation (1)
KRAS wild-type + NRAS wild-type + MSI-H/dMMR (1)
MLL-AFF1 fusion + NRAS mutation (1)
NRAS mutation + BRAF wild-type (1)
NRAS wild-type + NOTCH4 mutation (1)
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VERI cancer hierarchy
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NRAS Q61H
Hepatocellular Cancer
NRAS Q61H
Hepatocellular Cancer
sorafenib + BAY86-9766
Sensitive: C3 – Early Trials
sorafenib + BAY86-9766
Sensitive
:
C3
sorafenib + BAY86-9766
Sensitive: C3 – Early Trials
sorafenib + BAY86-9766
Sensitive
:
C3
NRAS Q61H
Melanoma
NRAS Q61H
Melanoma
nivolumab
Sensitive: C3 – Early Trials
nivolumab
Sensitive
:
C3
nivolumab
Sensitive: C3 – Early Trials
nivolumab
Sensitive
:
C3
NRAS Q61H
Melanoma
NRAS Q61H
Melanoma
ipilimumab
Sensitive: C4 – Case Studies
ipilimumab
Sensitive
:
C4
ipilimumab
Sensitive: C4 – Case Studies
ipilimumab
Sensitive
:
C4
NRAS Q61H
Multiple Myeloma
NRAS Q61H
Multiple Myeloma
bortezomib
Sensitive: D – Preclinical
bortezomib
Sensitive
:
D
bortezomib
Sensitive: D – Preclinical
bortezomib
Sensitive
:
D
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