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BIOMARKER:
NRG1 overexpression + ERBB3 expression
i
Other names:
ERBB3, HER3, LCCS2, V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3, NRG1, GGF, HGL, HRG, NDF, NRG1-IT2, Neuregulin 1, Heregulin
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Entrez ID:
2065
;
3084
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
ERBB3 R135C + TMB-H (1)
ERBB3 V104L + HER-2 negative (1)
ERBB3 amplification + ERBB3 mutation (1)
ERBB3 mutation + HER-2 amplification (1)
ERBB3-L (1)
POLE V1368M + ERBB3 G1271S + TNFAIP3 P714A + PRKN I69T + TSC2 G1399R + TMB-L (1)
CD74-NRG1 fusion + EGFR mutation + HER-2 mutation (1)
POMK-NRG1 fusion + KRAS mutation (1)
POMK‐NRG1 fusion + KRAS G12D (1)
ERBB3 R135C + TMB-H (1)
ERBB3 V104L + HER-2 negative (1)
ERBB3 amplification + ERBB3 mutation (1)
ERBB3 mutation + HER-2 amplification (1)
ERBB3-L (1)
POLE V1368M + ERBB3 G1271S + TNFAIP3 P714A + PRKN I69T + TSC2 G1399R + TMB-L (1)
CD74-NRG1 fusion + EGFR mutation + HER-2 mutation (1)
POMK-NRG1 fusion + KRAS mutation (1)
POMK‐NRG1 fusion + KRAS G12D (1)
›
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VERI cancer hierarchy
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NRG1 overexpression + ERBB3 expression
Head and Neck Cancer
NRG1 overexpression + ERBB3 expression
Head and Neck Cancer
lapatinib
Sensitive: D – Preclinical
lapatinib
Sensitive
:
D
lapatinib
Sensitive: D – Preclinical
lapatinib
Sensitive
:
D
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