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BIOMARKER:
PDGFRA D842V
i
Other names:
Platelet Derived Growth Factor Receptor Alpha, Platelet-Derived Growth Factor Receptor Alpha Polypeptide, Alpha-Type Platelet-Derived Growth Factor Receptor, CD140 Antigen-Like Family Member A, CD140a Antigen, PDGF-R-Alpha, PDGFR-2, PDGFR2, Alpha Platelet-Derived Growth Factor Receptor, Platelet-Derived Growth Factor Alpha Receptor, PDGFR-Alpha, RHEPDGFRA, CD140A
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Entrez ID:
5156
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
FIP1L1-PDGFRA fusion (4)
BCR exon 1-PDGFRA exon 13 fusion (1)
PDGFRA fusion (0)
FIP1L1-PDGFRA fusion (4)
BCR exon 1-PDGFRA exon 13 fusion (1)
PDGFRA fusion (0)
›
Related tests:
AYVAKIT® CDx test
therascreen PDGFRA RGQ PCR kit
AYVAKIT® CDx test
therascreen PDGFRA RGQ PCR kit
Associations
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VERI cancer hierarchy
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PDGFRA D842V
Gastrointestinal Stromal Tumor
PDGFRA D842V
Gastrointestinal Stromal Tumor
avapritinib
Sensitive: A1 - Approval
avapritinib
Sensitive
:
A1
avapritinib
Sensitive: A1 - Approval
avapritinib
Sensitive
:
A1
PDGFRA D842V
Gastrointestinal Stromal Tumor
PDGFRA D842V
Gastrointestinal Stromal Tumor
dasatinib
Sensitive: A2 - Guideline
dasatinib
Sensitive
:
A2
dasatinib
Sensitive: A2 - Guideline
dasatinib
Sensitive
:
A2
PDGFRA D842V
Gastric Cancer
PDGFRA D842V
Gastric Cancer
imatinib
Resistant: A2 - Guideline
imatinib
Resistant
:
A2
imatinib
Resistant: A2 - Guideline
imatinib
Resistant
:
A2
PDGFRA D842V
Gastrointestinal Stromal Tumor
PDGFRA D842V
Gastrointestinal Stromal Tumor
ARO-002
Sensitive: C2 – Inclusion Criteria
ARO-002
Sensitive
:
C2
ARO-002
Sensitive: C2 – Inclusion Criteria
ARO-002
Sensitive
:
C2
PDGFRA D842V
Gastrointestinal Stromal Tumor
PDGFRA D842V
Gastrointestinal Stromal Tumor
sunitinib
Resistant: C3 – Early Trials
sunitinib
Resistant
:
C3
sunitinib
Resistant: C3 – Early Trials
sunitinib
Resistant
:
C3
PDGFRA D842V
Gastrointestinal Stromal Tumor
PDGFRA D842V
Gastrointestinal Stromal Tumor
imatinib
Resistant: C3 – Early Trials
imatinib
Resistant
:
C3
imatinib
Resistant: C3 – Early Trials
imatinib
Resistant
:
C3
PDGFRA D842V
Gastrointestinal Stromal Tumor
PDGFRA D842V
Gastrointestinal Stromal Tumor
anlotinib
Sensitive: C4 – Case Studies
anlotinib
Sensitive
:
C4
anlotinib
Sensitive: C4 – Case Studies
anlotinib
Sensitive
:
C4
PDGFRA D842V
Gastrointestinal Stromal Tumor
PDGFRA D842V
Gastrointestinal Stromal Tumor
pimitespib
Sensitive: C4 – Case Studies
pimitespib
Sensitive
:
C4
pimitespib
Sensitive: C4 – Case Studies
pimitespib
Sensitive
:
C4
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