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BIOMARKER:
PMS2 mutation + MLH1 mutation
i
Other names:
MLH1, COCA2, FCC2, HNPCC, HNPCC2, MutL homolog 1, PMS2, PMS1 Homolog 2, Mismatch Repair System Component, PMS1 Homolog 2, Mismatch Repair Protein, Mismatch Repair Endonuclease PMS2, DNA Mismatch Repair Protein PMS2, PMS1 Protein Homolog 2, PMSL2, PMS2 Postmeiotic Segregation Increased 2, Postmeiotic Segregation Increased 2 Nirs Variant 6, PMS2 Postmeiotic Segregation Increased 2, HNPCC4, PMS2CL, MLH4
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Entrez ID:
4292
;
5395
Related biomarkers:
Expression
Mutation
CNA
Others
‹
MLH1 mutation (6)
PMS2 mutation (4)
MLH1 V384D (3)
PMS2 1144+1G>A (1)
MLH1 mutation (6)
PMS2 mutation (4)
MLH1 V384D (3)
PMS2 1144+1G>A (1)
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VERI cancer hierarchy
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PMS2 mutation + MLH1 mutation
Gastric Cancer
PMS2 mutation + MLH1 mutation
Gastric Cancer
nivolumab + ipilimumab
Sensitive: C3 – Early Trials
nivolumab + ipilimumab
Sensitive
:
C3
nivolumab + ipilimumab
Sensitive: C3 – Early Trials
nivolumab + ipilimumab
Sensitive
:
C3
PMS2 mutation + MLH1 mutation
Colorectal Cancer
PMS2 mutation + MLH1 mutation
Colorectal Cancer
nivolumab + ipilimumab
Sensitive: C3 – Early Trials
nivolumab + ipilimumab
Sensitive
:
C3
nivolumab + ipilimumab
Sensitive: C3 – Early Trials
nivolumab + ipilimumab
Sensitive
:
C3
PMS2 mutation + MLH1 mutation
Prostate Cancer
PMS2 mutation + MLH1 mutation
Prostate Cancer
nivolumab + ipilimumab
Sensitive: C4 – Case Studies
nivolumab + ipilimumab
Sensitive
:
C4
nivolumab + ipilimumab
Sensitive: C4 – Case Studies
nivolumab + ipilimumab
Sensitive
:
C4
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