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DRUG:

sabatolimab (MBG453)

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Company:

Novartis

Drug class:

TIM-3 antagonist

Related drugs:

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No biomarker	Myelodysplastic Syndrome	No biomarker	Myelodysplastic Syndrome	MBG453 Sensitive: B - Late Trials MBG453 Sensitive : B	MBG453 Sensitive: B - Late Trials MBG453 Sensitive : B
TP53 mutation	Acute Myelogenous Leukemia	TP53 mutation	Acute Myelogenous Leukemia	MBG453 Sensitive: C3 – Early Trials MBG453 Sensitive : C3	MBG453 Sensitive: C3 – Early Trials MBG453 Sensitive : C3
TP53 mutation	Myelodysplastic Syndrome	TP53 mutation	Myelodysplastic Syndrome	MBG453 Sensitive: C3 – Early Trials MBG453 Sensitive : C3	MBG453 Sensitive: C3 – Early Trials MBG453 Sensitive : C3
TP53 mutation	Myelodysplastic Syndrome	TP53 mutation	Myelodysplastic Syndrome	azacitidine + MBG453 Sensitive: C3 – Early Trials azacitidine + MBG453 Sensitive : C3	azacitidine + MBG453 Sensitive: C3 – Early Trials azacitidine + MBG453 Sensitive : C3
TP53 mutation	Myelodysplastic Syndrome	TP53 mutation	Myelodysplastic Syndrome	decitabine + MBG453 Sensitive: C3 – Early Trials decitabine + MBG453 Sensitive : C3	decitabine + MBG453 Sensitive: C3 – Early Trials decitabine + MBG453 Sensitive : C3
MECOM rearrangement	Myelodysplastic Syndrome	MECOM rearrangement	Myelodysplastic Syndrome	MBG453 Sensitive: C4 – Case Studies MBG453 Sensitive : C4	MBG453 Sensitive: C4 – Case Studies MBG453 Sensitive : C4