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BIOMARKER:
STAT6 deletion + HER-2 overexpression
i
Other names:
STAT6, Signal transducer and activator of transcription 6, Transcription factor IL-4 STAT, D12S1644, ERBB2, CD340, HER-2, HER2, NEU, NGL, V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
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Entrez ID:
2064
;
6778
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
HER-2 amplification (129)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
HER-2 amplification + MET amplification (1)
HER-2 amplification + PTEN deletion (1)
HER-2 exon 19 deletion (1)
MYC amplification + HER-2 amplification (1)
HER-2 amplification + CDK12 amplification (0)
YES1 amplification + HER-2 amplification (0)
STAT6 deletion (0)
HER-2 amplification (129)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
HER-2 amplification + MET amplification (1)
HER-2 amplification + PTEN deletion (1)
HER-2 exon 19 deletion (1)
MYC amplification + HER-2 amplification (1)
HER-2 amplification + CDK12 amplification (0)
YES1 amplification + HER-2 amplification (0)
STAT6 deletion (0)
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STAT6 deletion + HER-2 overexpression
HER2 Positive Breast Cancer
STAT6 deletion + HER-2 overexpression
HER2 Positive Breast Cancer
trastuzumab
Resistant: C3 – Early Trials
trastuzumab
Resistant
:
C3
trastuzumab
Resistant: C3 – Early Trials
trastuzumab
Resistant
:
C3
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