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BIOMARKER:
TPBG underexpression + HER-2 overexpression
i
Other names:
TPBG, Trophoblast Glycoprotein, 5T4, 5T4 Oncofetal Trophoblast Glycoprotein, Wnt-Activated Inhibitory Factor, 5T4 Oncotrophoblast Glycoprotein, 5T4 Oncofetal Antigen, WAIF1, M6P1, 5T4-AG, 5T4AG, ERBB2, CD340, HER-2, HER2, NEU, NGL, V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
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Entrez ID:
2064
;
7162
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
HER-2 amplification (129)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
HER-2 amplification + MET amplification (1)
HER-2 amplification + PTEN deletion (1)
HER-2 exon 19 deletion (1)
MYC amplification + HER-2 amplification (1)
HER-2 amplification + CDK12 amplification (0)
YES1 amplification + HER-2 amplification (0)
HER-2 amplification (129)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
HER-2 amplification + MET amplification (1)
HER-2 amplification + PTEN deletion (1)
HER-2 exon 19 deletion (1)
MYC amplification + HER-2 amplification (1)
HER-2 amplification + CDK12 amplification (0)
YES1 amplification + HER-2 amplification (0)
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Trials
VERI cancer hierarchy
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TPBG underexpression + HER-2 overexpression
Gastric Cancer
TPBG underexpression + HER-2 overexpression
Gastric Cancer
KRLS-004
Sensitive: D – Preclinical
KRLS-004
Sensitive
:
D
KRLS-004
Sensitive: D – Preclinical
KRLS-004
Sensitive
:
D
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