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DRUG CLASS:

XPO1 inhibitor

DRUG CLASS:

XPO1 inhibitor

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No biomarker	Multiple Myeloma	No biomarker	Multiple Myeloma	selinexor Sensitive: A1 - Approval selinexor Sensitive : A1	selinexor Sensitive: A1 - Approval selinexor Sensitive : A1
No biomarker	Diffuse Large B Cell Lymphoma	No biomarker	Diffuse Large B Cell Lymphoma	selinexor Sensitive: A1 - Approval selinexor Sensitive : A1	selinexor Sensitive: A1 - Approval selinexor Sensitive : A1
No biomarker	Multiple Myeloma	No biomarker	Multiple Myeloma	selinexor + pomalidomide Sensitive: A2 - Guideline selinexor + pomalidomide Sensitive : A2	selinexor + pomalidomide Sensitive: A2 - Guideline selinexor + pomalidomide Sensitive : A2
No biomarker	Multiple Myeloma	No biomarker	Multiple Myeloma	selinexor + daratumumab Sensitive: A2 - Guideline selinexor + daratumumab Sensitive : A2	selinexor + daratumumab Sensitive: A2 - Guideline selinexor + daratumumab Sensitive : A2
No biomarker	Multiple Myeloma	No biomarker	Multiple Myeloma	selinexor + carfilzomib Sensitive: A2 - Guideline selinexor + carfilzomib Sensitive : A2	selinexor + carfilzomib Sensitive: A2 - Guideline selinexor + carfilzomib Sensitive : A2
Chr del(17p)	Multiple Myeloma	Chr del(17p)	Multiple Myeloma	bortezomib + selinexor Sensitive: B - Late Trials bortezomib + selinexor Sensitive : B	bortezomib + selinexor Sensitive: B - Late Trials bortezomib + selinexor Sensitive : B
No biomarker	Multiple Myeloma	No biomarker	Multiple Myeloma	selinexor Sensitive: B - Late Trials selinexor Sensitive : B	selinexor Sensitive: B - Late Trials selinexor Sensitive : B
No biomarker	Liposarcoma	No biomarker	Liposarcoma	selinexor Sensitive: B - Late Trials selinexor Sensitive : B	selinexor Sensitive: B - Late Trials selinexor Sensitive : B
GRM1 overexpression	Liposarcoma	GRM1 overexpression	Liposarcoma	selinexor Sensitive: B - Late Trials selinexor Sensitive : B	selinexor Sensitive: B - Late Trials selinexor Sensitive : B
CALB1 underexpression	Liposarcoma	CALB1 underexpression	Liposarcoma	selinexor Sensitive: B - Late Trials selinexor Sensitive : B	selinexor Sensitive: B - Late Trials selinexor Sensitive : B
CALB1 deletion	Liposarcoma	CALB1 deletion	Liposarcoma	selinexor Sensitive: B - Late Trials selinexor Sensitive : B	selinexor Sensitive: B - Late Trials selinexor Sensitive : B
TP53 wild-type	Endometrial Cancer	TP53 wild-type	Endometrial Cancer	selinexor Sensitive: B - Late Trials selinexor Sensitive : B	selinexor Sensitive: B - Late Trials selinexor Sensitive : B