COMPANY:

Genetron Health

"Genetron Holdings Limited...announced today the completion of its merger (the 'Merger') with Genetron New Co Limited ('Merger Sub'), pursuant to the previously announced agreement and plan of merger, dated as of October 11, 2023 (the 'Merger Agreement'), among the Company, New Genetron Holding Limited ('Parent') and Merger Sub. As a result of the Merger, the Company has become a wholly owned subsidiary of Parent and will cease to be a publicly traded company."

"Genetron Holdings Limited...announced today that it has entered into a definitive Agreement and Plan of Merger (the 'Merger Agreement') with New Genetron Holding Limited ('Parent') and Genetron New Co Limited ('Merger Sub'), a wholly-owned subsidiary of Parent."

"CStone Pharmaceuticals...announced that the AYVAKIT® (avapritinib) companion diagnostic (CDx) kit, known as 'Human platelet-derived growth factor receptor alpha (PDGFRA) Gene D842V Mutation Detection Kit', developed in partnership with Genetron Holdings Limited (Genetron Health) has been approved by the China National Medical Products Administration (NMPA). This CDx kit is the first companion diagnostic product co-developed through the bridging pathway in China to gain regulatory approval following the release of the companion diagnostic guidelines by NMPA. It is used to detect PDGFRA gene mutations in gastrointestinal stromal tumor (GIST) for patients receiving treatment with AYVAKIT."

"Genetron Holdings Limited...announced College of American Pathologists (CAP) Accreditation for its laboratory in Maryland, U.S...CAP Accreditation is designed to help laboratories maintain the accuracy of test results and ensure accurate patient diagnosis, meet required regulatory standards and maintain industry-leading best practices. The Maryland laboratory joins the Company’s main lab in Beijing as its second lab that is both CAP and CLIA accredited. With the accreditation the company strengthens its US arm of drug development services conducting discovery and translational research, clinical trial execution and corresponding companion diagnostics development."

"Genetron Holdings Limited...announced the release of 10 research results at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting...Based on Genetron Health’s patented One-Step™ Seq Method and core products such as Onco PanScan™, the results aimed to contribute to the scientific research and clinical practice of full-cycle cancer management."

"Genetron Holdings Limited...announced it has obtained a CE Mark for its FusionScan Plus Kit, an integrated DNA and RNA NGS-based assay for simultaneously detecting multiple gene mutations and fusions with lower thresholds, (Registration number: DE/CA20/01-IVD-Luxuslebenswelt-886/22)."

"Genetron Holdings Limited...today announced it has received a CE Mark for its proprietary Human B Lymphocyte Minimal Residual Disease Detection Kit (Reversible Termination Sequencing Method), which is also known as Seq-MRD® (Registration Number: DE/CA20/01-IVD-Luxuslebenswelt-190/22)...Based on high-throughput next generation sequencing (NGS) technology, Seq-MRD® assay is intended to test the CDR3 regional sequence of the IgH/K/L gene of the B cell receptor (BCR) in bone marrow samples collected from patients with B lymphpocytic leukemia (B-ALL/CLL) and multiple myeloma (MM) before and after the treatment. By screening out significant and specific clonal rearrangement form in a patient's tumor cells, this approach can detect minimal residual disease and provide a reference for the follow-up treatment of cancer survivors."

"Genetron Holdings Limited...announced the release of 17 research results at the American Association for Cancer Research Annual Meeting 2022 (AACR 2022)...The results emerged from joint studies that Genetron Health conducted with more than 20 leading hospitals in China, which leveraged the Company's 'One-step Seq' patented technology, core products such as the multi-gene NGS panel testing - Onco PanScan™ and the comprehensive sarcoma gene testing - Onco PanScan plus™."

"Genetron Holdings Limited...announced that a research piece titled 'Integrated analysis of circulating tumor cells and circulating tumor DNA to detect minimal residual disease in hepatocellular carcinoma' has been published in a highly impactful journal, Clinical and Translational Medicine (Impact Factor: 11.5)...The data showed that the performance of cfDNA based tumor-naïve assays could be further improved by combining with CTCs. These findings underscore the importance of CTC and ctDNA integration in recurrence prediction and could also provide a reference for selecting strategies for HCC MRD surveillance."

Investor Presentation

Investor Presentation

Investor Presentation