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    DRUG:

    KN5501

    i
    Other names: KN5501, Anti-CD19 CAR NK Cells
    Associations

    News

    Trials
    Company:
    Rui Therapeutics
    Drug class:
    CD19 inhibitor, NK cell stimulant
    Related drugs:
    Associations

    News

    Trials
    3ms
    An Exploratory Clinical Study of CD19 CAR NK Cell Injection for the Treatment of Relapsed/Refractory Autoimmune Diseases (clinicaltrials.gov)
    P1, N=72, Recruiting, Changhai Hospital | Trial primary completion date: Jun 2025 --> Dec 2025
    Trial primary completion date
    |
    cyclophosphamide • fludarabine IV • KN5501
    7ms
    An Exploratory Clinical Study of Anti-CD19 CAR NK Cells in the Treatment of Systemic Lupus Erythematosus (clinicaltrials.gov)
    P1, N=36, Recruiting, Changhai Hospital | Trial completion date: Aug 2026 --> Aug 2027
    Trial completion date
    |
    cyclophosphamide • fludarabine IV • KN5501
    7ms
    An Exploratory Clinical Study of CD19 CAR NK Cells for the Treatment of Refractory Antisynthetase Antibody Syndrome and Rheumatoid Arthritis (clinicaltrials.gov)
    P1, N=24, Recruiting, The First Affiliated Hospital with Nanjing Medical University | Not yet recruiting --> Recruiting | Initiation date: Oct 2024 --> May 2025
    Enrollment open • Trial initiation date
    |
    cyclophosphamide • fludarabine IV • KN5501
    7ms
    An Clinical Study of CD19 CAR NK Cells for the Treatment of Refractory Primary Immune Thrombocytopenia (clinicaltrials.gov)
    P1, N=9, Recruiting, Changzhou No.2 People's Hospital | Not yet recruiting --> Recruiting | Trial completion date: Mar 2026 --> Jul 2026 | Trial primary completion date: Mar 2025 --> Jul 2025
    Enrollment open • Trial completion date • Trial primary completion date
    |
    cyclophosphamide • fludarabine IV • KN5501
    7ms
    An Exploratory Clinical Study of Anti-CD19 CAR NK Cells in the Treatment of Systemic Lupus Erythematosus (clinicaltrials.gov)
    P1, N=36, Recruiting, Changhai Hospital | N=12 --> 36 | Trial completion date: Aug 2025 --> Aug 2026 | Trial primary completion date: Aug 2024 --> Aug 2026
    Enrollment change • Trial completion date • Trial primary completion date
    |
    cyclophosphamide • fludarabine IV • KN5501
    1year
    An Exploratory Clinical Study of CD19 CAR NK Cells for the Treatment of Refractory Antisynthetase Antibody Syndrome and Rheumatoid Arthritis (clinicaltrials.gov)
    P1, N=24, Not yet recruiting, The First Affiliated Hospital with Nanjing Medical University
    New P1 trial
    |
    cyclophosphamide • KN5501
    over1year
    An Clinical Study of CD19 CAR NK Cells for the Treatment of Refractory Primary Immune Thrombocytopenia (clinicaltrials.gov)
    P1, N=9, Not yet recruiting, Changzhou No.2 People's Hospital | Initiation date: Mar 2024 --> Aug 2024
    Trial initiation date
    |
    cyclophosphamide • KN5501
    over1year
    An Exploratory Clinical Study of Anti-CD19 CAR NK Cells in the Treatment of Systemic Lupus Erythematosus (clinicaltrials.gov)
    P1, N=12, Recruiting, Changhai Hospital | Trial completion date: Aug 2026 --> Aug 2025 | Initiation date: Jul 2024 --> Aug 2023 | Trial primary completion date: Aug 2025 --> Aug 2024
    Trial completion date • Trial initiation date • Trial primary completion date
    |
    cyclophosphamide • KN5501
    over1year
    An Exploratory Clinical Study of Anti-CD19 CAR NK Cell (KN5501) in the Treatment of Relapsed/Refractory Immune Nephropathy (clinicaltrials.gov)
    P1, N=36, Recruiting, Changhai Hospital | Not yet recruiting --> Recruiting
    Enrollment open
    |
    cyclophosphamide • KN5501
    over1year
    An Exploratory Clinical Study of Anti-CD19 CAR NK Cells in the Treatment of Systemic Lupus Erythematosus (clinicaltrials.gov)
    P1, N=12, Recruiting, Changhai Hospital | Trial completion date: Aug 2025 --> Aug 2026 | Initiation date: Aug 2023 --> Jul 2024 | Trial primary completion date: Aug 2024 --> Aug 2025
    Trial completion date • Trial initiation date • Trial primary completion date
    |
    cyclophosphamide • KN5501
    over1year
    An Exploratory Clinical Study of Anti-CD19 CAR NK Cell (KN5501) in the Treatment of Relapsed/Refractory Immune Nephropathy (clinicaltrials.gov)
    P1, N=36, Not yet recruiting, Changhai Hospital
    New P1 trial
    |
    cyclophosphamide • KN5501
    almost3years
    The Study of Anti-CD19 CAR NK Cells in the Treatment of Relapsed/Refractory Diffuse Large B Cell Lymphoma (clinicaltrials.gov)
    P1, N=12, Not yet recruiting, Changhai Hospital
    New P1 trial
    |
    CD19 (CD19 Molecule)
    |
    CD19 positive
    |
    cyclophosphamide • KN5501