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DRUG:

AU7R-104

i
Other names: AU7R-104, AUR-104
Associations
Trials
Company:
Dr. Reddy’s
Drug class:
CD47 inhibitor
Associations
Trials
5d
A Study of AUR104 in Patients With Relapsed/Refractory Lymphoid Malignancies (VIJAY-1) (clinicaltrials.gov)
P1, N=9, Terminated, Aurigene Discovery Technologies Limited | N=42 --> 9 | Trial completion date: Jan 2027 --> Feb 2026 | Recruiting --> Terminated | Trial primary completion date: Nov 2026 --> Feb 2026; Patient recruitment problems
Enrollment change • Trial completion date • Trial termination • Trial primary completion date
|
AU7R-104 • XL114
over1year
New P1 trial
|
AU7R-104 • XL114
5years
[VIRTUAL] Discovery and preclinical evaluation of a novel covalent inhibitor of FABP5 for cancer therapy (AACR 2021)
In summary, we have identified a novel covalent FABP5 inhibitor with optimized properties that showed anti-tumor activity in in vitro and in vivo models with acceptable safety profile. The data presented here strongly support clinical development of AUR104.
Preclinical
|
IL6 (Interleukin 6) • IL10 (Interleukin 10) • MALT1 (MALT1 Paracaspase)
|
AU7R-104