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BIOMARKER:
BCR-ABL1 F359C
i
Other names:
BCR, BCR Activator Of RhoGEF And GTPase, BCR, RhoGEF And GTPase Activating Protein, Breakpoint Cluster Region Protein, Renal Carcinoma Antigen NY-REN-26, Breakpoint Cluster Region, D22S11, BCR1, BCR/FGFR1 Chimera Protein, FGFR1/BCR Chimera Protein, D22S662, ALL, CML, PHL, ABL proto-oncogene 1, ABL, c-ABL, JTK7, p150, ABL1
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Entrez ID:
25
;
613
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
ABL1 T315I (5)
ABL1 E255K (2)
ABL1 G250E + ABL1 D276G + ABL1 T315I (2)
ABL1 D276G (1)
ABL1 F317L (1)
ABL1 F359V (1)
ABL1 G250E (1)
ABL1 L387M (1)
ABL1 M351T (1)
ABL1 T315I + ABL1 M351T + ABL1 L387M (1)
ABL1 Y253H (1)
BCR-ABL1 A337T (1)
BCR-ABL1 P465S (1)
BCR-ABL1 Q252H + BCR-ABL1 V299L (1)
BCR-ABL1 T315L (1)
BCR-ABL1 Y253H + BCR-ABL1 T315I (1)
ABL1 T315I (5)
ABL1 E255K (2)
ABL1 G250E + ABL1 D276G + ABL1 T315I (2)
ABL1 D276G (1)
ABL1 F317L (1)
ABL1 F359V (1)
ABL1 G250E (1)
ABL1 L387M (1)
ABL1 M351T (1)
ABL1 T315I + ABL1 M351T + ABL1 L387M (1)
ABL1 Y253H (1)
BCR-ABL1 A337T (1)
BCR-ABL1 P465S (1)
BCR-ABL1 Q252H + BCR-ABL1 V299L (1)
BCR-ABL1 T315L (1)
BCR-ABL1 Y253H + BCR-ABL1 T315I (1)
›
Associations
(6)
News
Trials
Filter by
Latest
11ms
Identification of novel BCR::ABL1 kinase domain mutation in patients with chronic myeloid leukaemia and imatinib resistance. (PubMed, Malays J Pathol)
Mutational analysis is recommended to identify patients at risk of disease progression. Therefore, early detection of such mutations may allow timely treatment intervention to prevent or overcome resistance.
11 months ago
Journal
|
ABL1 (ABL proto-oncogene 1)
|
BCR-ABL1 E255K • BCR-ABL1 F317L • BCR-ABL1 Y253H • BCR-ABL1 F359C • ABL1 E255K • BCR-ABL1 E459K • ABL1 F317L • ABL1 F359V • ABL1 Y253H • BCR-ABL1 F359
|
imatinib
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