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    BIOMARKER:

    CCND3 deletion

    i
    Other names: CCND3, Cyclin D3, G1/S-Specific Cyclin-D3, D3-Type Cyclin
    Entrez ID:
    896
    Related biomarkers:
    Mutation
    1year
    Downregulated CCND3 Is a Key Event Driving Lung Adenocarcinoma Metastasis during Acquired Cisplatin Resistance. (PubMed, Int J Biol Sci)
    This, in turn, promoted EMT, facilitating cytoskeleton remodeling-stimulated metastasis and chemoresistance to DDP. Overall, these findings provided a new perspective on the role of CCND3 in LUAD progression and acquired cisplatin resistance.
    Journal
    |
    VIM (Vimentin) • CCND3 (Cyclin D3)
    |
    VIM expression • CCND3 deletion
    |
    cisplatin