^
2d
Multiple Ascending-Dose Study of XmAb®27564 in Patients With Psoriasis or Atopic Dermatitis (clinicaltrials.gov)
P1, N=23, Terminated, Xencor, Inc. | N=128 --> 23 | Active, not recruiting --> Terminated; Business Decision
Enrollment change • Trial termination
8d
A Platform Study to Evaluate Investigational Therapies in Chronic Hepatitis B Infection (clinicaltrials.gov)
P1/2, N=33, Completed, Vir Biotechnology, Inc. | Active, not recruiting --> Completed | N=150 --> 33 | Trial completion date: Mar 2027 --> Aug 2025
Trial completion • Enrollment change • Trial completion date
15d
INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM) (clinicaltrials.gov)
P1/2, N=52, Active, not recruiting, Inovio Pharmaceuticals | Trial completion date: Dec 2025 --> Dec 2026 | Trial primary completion date: Dec 2025 --> Dec 2026
Trial completion date • Trial primary completion date
|
temozolomide • Libtayo (cemiplimab-rwlc) • INO-5401 • rocakinogene sifuplasmid (INO-9012)
21d
A Study to Evaluate Tobevibart + Elebsiran in Chronic HDV Infection (clinicaltrials.gov)
P3, N=124, Active, not recruiting, Vir Biotechnology, Inc. | Recruiting --> Active, not recruiting
Enrollment closed
24d
All-Trans Retinoic Acid (ATRA) and Atezolizumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer (clinicaltrials.gov)
P1, N=18, Active, not recruiting, Dwight Owen | Suspended --> Active, not recruiting | Trial completion date: Oct 2025 --> Jan 2026 | Trial primary completion date: Oct 2025 --> Jan 2026
Enrollment closed • Trial completion date • Trial primary completion date
|
PD-L1 (Programmed death ligand 1) • ALK (Anaplastic lymphoma kinase)
|
Tecentriq (atezolizumab) • Vesanoid (tretinoin)
1m
Enrollment change
|
Rituxan (rituximab) • Tab-cel (tabelecleucel)
1m
MARCH: Study of VIR-2218, VIR-3434, and/or PEG-IFNα in Subjects With Chronic Hepatitis B Virus Infection (clinicaltrials.gov)
P2, N=244, Active, not recruiting, Vir Biotechnology, Inc. | Trial completion date: Jun 2027 --> Mar 2026 | Trial primary completion date: Jun 2027 --> Mar 2026
Trial completion date • Trial primary completion date
2ms
Trial suspension
|
PD-L1 (Programmed death ligand 1) • ALK (Anaplastic lymphoma kinase)
|
Tecentriq (atezolizumab) • Vesanoid (tretinoin)
2ms
Trial primary completion date
|
Rituxan (rituximab) • Tab-cel (tabelecleucel)
2ms
MELODY-1: A Phase 1b Trial to Evaluate Safety of MB097 in Combination With Pembrolizumab in Melanoma Patients (clinicaltrials.gov)
P1, N=41, Active, not recruiting, Microbiotica Ltd | Recruiting --> Active, not recruiting
Enrollment closed
|
Keytruda (pembrolizumab)
2ms
Trial primary completion date • Platinum resistant
|
Avastin (bevacizumab) • cisplatin • carboplatin • gemcitabine • albumin-bound paclitaxel • pegylated liposomal doxorubicin • olvimulogene nanivacirepvec (GL-ONC1)
3ms
Study of ET140203 T Cells in Adults With Advanced Hepatocellular Carcinoma (ARYA-1) (clinicaltrials.gov)
P1, N=8, Terminated, Eureka Therapeutics Inc. | Phase classification: P1/2 --> P1
Phase classification
|
AFP (Alpha-fetoprotein)
|
ET140203