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    DRUG:

    FF-10501-01

    i
    Other names: FF-10501-01, FF-10501, FF 10501
    Associations

    News

    Trials
    Company:
    Fujifilm Holdings, Strategia Therap
    Drug class:
    IMPDH inhibitor, Cell differentiation stimulant
    Related drugs:
    Associations

    News

    Trials
    9ms
    Study of FF-10501-01 in Patients With Relapsed or Refractory Hematological Malignancies (clinicaltrials.gov)
    P1/2, N=55, Completed, Fujifilm Pharmaceuticals U.S.A., Inc. | N=41 --> 55
    Enrollment change
    |
    FF-10501-01
    over5years
    FF-10501 induces caspase-8-mediated apoptotic and endoplasmic reticulum stress-mediated necrotic cell death in hematological malignant cells. (PubMed, Int J Hematol)
    FF-10501 induced necrotic cell death via endoplasmic reticulum stress in OCI-AML3 cells. The present study is the first to identify intracellular pathways involved in FF-10501-induced cell death.
    Journal
    |
    CASP8 (Caspase 8)
    |
    FF-10501-01