^
    1d
    Role of Combination Therapy of Glucose Insulin Potassium Infusion (GIK), Intravenous Hydrocortisone and Oral Sevelamer in Treatment of Acute Aluminum Phosphide Poisoned Cases Admitted to Intensive Care Unit (ICU) at Sohag University Hospitals. (clinicaltrials.gov)
    P=N/A, N=74, Not yet recruiting, Sohag University
    New trial
    1d
    Dexamethasone for Ureteral STent Symptoms (DUSTS) (clinicaltrials.gov)
    P1/2, N=70, Not yet recruiting, The Methodist Hospital Research Institute | Trial completion date: Jan 2026 --> Apr 2027 | Initiation date: May 2025 --> Apr 2026 | Trial primary completion date: Dec 2025 --> Dec 2026
    Trial completion date • Trial initiation date • Trial primary completion date
    |
    dexamethasone injection
    2d
    An abnormal immune response masquerading as infectious conditions. (PubMed, SAGE Open Med Case Rep)
    The patient's fever resolved after dexamethasone administration, supporting an immune-mediated process. She subsequently developed recurrent fever, rash, and oral ulcers, which responded rapidly to intravenous corticosteroids, followed by a steroid taper.
    Journal
    |
    IL18 (Interleukin 18)
    |
    dexamethasone
    2d
    Vitamin C With Steroids for Gastrointestinal GVHD (clinicaltrials.gov)
    P1, N=35, Not yet recruiting, Baylor College of Medicine | Initiation date: Jan 2026 --> Jun 2026
    Trial initiation date
    |
    methylprednisolone sodium succinate
    3d
    Hydrocortisone and Fludrocortisone for the Treatment of Septic Shock (clinicaltrials.gov)
    P4, N=336, Recruiting, Northern Jiangsu People's Hospital | Not yet recruiting --> Recruiting
    Enrollment open
    3d
    ATLAS: Trial of Carfilzomib, Lenalidomide, Dexamethasone Versus Lenalidomide Alone After Stem-cell Transplant for Multiple Myeloma (clinicaltrials.gov)
    P3, N=180, Active, not recruiting, University of Chicago | Trial completion date: Nov 2026 --> Nov 2027 | Trial primary completion date: Nov 2025 --> Nov 2027
    Trial completion date • Trial primary completion date
    |
    lenalidomide • carfilzomib • dexamethasone
    3d
    Rapidly Progressive Overlap of Immune Checkpoint Inhibitor-Induced Myositis and Myasthenia Gravis: Diagnostic and Therapeutic Challenges. (PubMed, Cureus)
    We report a fulminant case of overlap syndrome involving ICI-induced myositis and myasthenia gravis in a 72-year-old man receiving ipilimumab-nivolumab for hepatocellular carcinoma and recurrent renal cell carcinoma...Despite prompt intensive care admission and treatment with high-dose intravenous methylprednisolone and intravenous immunoglobulin, only partial clinical improvement was achieved. The subsequent development of aspiration pneumonia led to acute respiratory and hepatic failure, culminating in death. This case underscores the aggressive clinical trajectory and high mortality of ICI-related neuromuscular overlap syndromes, highlighting the critical need for early recognition, rapid immunosuppression, and multidisciplinary management.
    Journal • Checkpoint inhibition
    |
    MB (Myoglobin)
    |
    Opdivo (nivolumab) • Yervoy (ipilimumab) • methylprednisolone sodium succinate
    4d
    CAC-PPCL-001: A Study of VRD-based Regimen Combined With CART-ASCT-CART2 Treatment in Patients With Primary Plasma Cell Leukemia (clinicaltrials.gov)
    P2, N=20, Recruiting, Institute of Hematology & Blood Diseases Hospital, China | Trial primary completion date: Apr 2025 --> Jun 2026
    Trial primary completion date
    |
    lenalidomide • bortezomib • dexamethasone
    4d
    EXAFIP2: Glucocorticoids Versus Placebo for the Treatment of Acute Exacerbation of Idiopathic Pulmonary Fibrosis (clinicaltrials.gov)
    P3, N=110, Recruiting, Fondation Hôpital Saint-Joseph | Trial primary completion date: Oct 2025 --> Mar 2026
    Trial primary completion date
    |
    prednisone • methylprednisolone sodium succinate
    5d
    TKA: Oral vs Intravenous Dexamethasone in Total Knee Arthroplasty (clinicaltrials.gov)
    P=N/A, N=99, Not yet recruiting, Haseki Training and Research Hospital
    New trial
    |
    dexamethasone • dexamethasone injection
    6d
    BUS-006/RAP: A phase II, double-blind, randomised, placebo-controlled trial to evaluate the efficacy and tolerability of a rectal treatment with budesonide suppositories versus placebo for amelioration of acute radiation proctitis symptoms (2024-519359-27-00)
    P1/2, N=160, Not yet recruiting, Dr. Falk Pharma GmbH
    New P1/2 trial
    7d
    A comprehensive analysis of common cytogenetic abnormalities in multiple myeloma: from basic research to clinical applications. (PubMed, Pathology)
    Among patients receiving bortezomib, lenalidomide, and dexamethasone (VRd) induction therapy, those with cytogenetic abnormalities showed significantly lower deep response rates (complete response + very good partial response). Furthermore, RB1 deletion or D13S319 deletion combined with other high-risk indicators further shortened PFS. These findings indicate that integrating expanded cytogenetic markers optimises MM risk stratification and provides a basis for individualised treatment strategies.
    Journal
    |
    TP53 (Tumor protein P53) • RB1 (RB Transcriptional Corepressor 1) • IGH (Immunoglobulin Heavy Locus) • B2M (Beta-2-microglobulin)
    |
    TP53 deletion • RB1 deletion
    |
    lenalidomide • bortezomib • dexamethasone