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BIOMARKER:
KIT D820A
i
Other names:
KIT, KIT proto-oncogene receptor tyrosine kinase, C-Kit, CD117, PBT, SCFR, Stem Cell Factor Receptor, V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
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Entrez ID:
3815
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
KIT amplification (2)
KIT amplification (2)
›
Associations
(1)
News
Trials
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Latest
over2years
Activity of Anlotinib in the Second-Line Therapy of Metastatic Gastrointestinal Stromal Tumors: A Prospective, Multicenter, In Vitro Study. (PubMed, Oncologist)
Anlotinib showed moderate antitumor activity in drug-resistant GIST cell lines in vitro, and good PFS and better tolerance in second-line therapy study.
over 2 years ago
Preclinical • Clinical Trial,Phase II • Journal • Stroma • Metastases
|
KIT (KIT proto-oncogene, receptor tyrosine kinase)
|
KIT mutation • KIT N822K • KIT exon 13 mutation • KIT V654A • KIT D820A
|
imatinib • Focus V (anlotinib) • sunitinib
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