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DRUG:

PT150

i
Other names: PT150, ORG34517, SCH-900636
Associations
Trials
Company:
The Pop Test & Palisades Therap
Drug class:
Androgen receptor inhibitor, GCR antagonist
Associations
Trials
8ms
PT150 Drug for Use in Alcohol Use Disorder (clinicaltrials.gov)
P1, N=34, Recruiting, Pop Test Oncology LLC | Not yet recruiting --> Recruiting
Enrollment open
|
PT150
1year
PT150 Drug for Use in Alcohol Use Disorder (clinicaltrials.gov)
P1, N=34, Not yet recruiting, Pop Test Oncology LLC
New P1 trial
|
PT150
over5years
[VIRTUAL] Pan-cancer analysis to identify a novel class of glucocorticoid and androgen receptor antagonists with potent anti-tumor activity. (ASCO 2020)
In addition, both PT150 and PT157 significantly increased nab-paclitaxel sensitivity in nab-paclitaxel-resistant isogenic PDAC cells. Our work has identified previously undescribed mechanisms of oncogenesis in several cancer types, as well as an efficacious class of novel compounds with the potential to inhibit them. Research Funding: Palisades Therapeutics/Pop Test Oncology LLC
Pan tumor
|
AR (Androgen receptor)
|
albumin-bound paclitaxel • PT150