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    DRUG CLASS:

    Serine protease inhibitor

    Related drugs:
    2d
    TRACES: Tranexamic Acid to Reduce Blood Loss in Hemorrhagic Caesarean Delivery (clinicaltrials.gov)
    P4, N=225, Completed, University Hospital, Lille | Terminated --> Completed
    Trial completion
    4d
    ASCOT: Effect on Post-operative Pain of Tranexamic Acid Injection During Shoulder Surgery (clinicaltrials.gov)
    P3, N=220, Completed, Elsan | Not yet recruiting --> Completed
    Trial completion
    9d
    Comparison of Anticoagulant Effects of Different Doses of Nafamostat in Continuous Renal Replacement Therapy (CRRT) in the Intensive Care Unit (ICU) (clinicaltrials.gov)
    P2, N=92, Recruiting, Zhujiang Hospital | Not yet recruiting --> Recruiting
    Enrollment open
    |
    nafamostat
    27d
    BIRCH: A Study to Evaluate the Safety, Tolerability and the Effects of Ixodes Ricinus-Contact Phase Inhibitor (Ir-CPI) in Adult Patients With Spontaneous Intracerebral Haemorrhage (clinicaltrials.gov)
    P2, N=23, Active, not recruiting, Bioxodes S.A. | Trial primary completion date: Aug 2025 --> Mar 2026
    Trial primary completion date
    1m
    CamKid: Effect Camostat for Kidney Protection in Chronic Kidney Disease (clinicaltrials.gov)
    P2, N=40, Completed, Odense University Hospital | Recruiting --> Completed
    Trial completion
    1m
    Comparison of Anticoagulant Effects of Different Doses of Nafamostat in Continuous Renal Replacement Therapy (CRRT) in the Intensive Care Unit (ICU) (clinicaltrials.gov)
    P2, N=92, Not yet recruiting, Zhujiang Hospital
    New P2 trial
    |
    nafamostat
    1m
    AMBP gene activation promotes cholangiocarcinoma progression through the WNT/β-catenin signaling pathway: Regulatory effect of polysaccharides from Auricularia auricula-judae. (PubMed, Medicine (Baltimore))
    High AMBP expression associates with CCA tumorigenesis, immunosuppression, and poor prognosis, acting via WNT. Huaier polysaccharide reverses CCA malignancy by inhibiting AMBP, reducing invasiveness/metastasis and improving prognosis.
    Journal
    |
    MYC (V-myc avian myelocytomatosis viral oncogene homolog) • CCND1 (Cyclin D1)
    2ms
    Single Dose Study, Pharmacokinetics of Oxycodone and PF614 Co-Administered With Nafamostat (PF614-MPAR-102) (clinicaltrials.gov)
    P1, N=30, Recruiting, Ensysce Biosciences | N=50 --> 30 | Trial completion date: Mar 2026 --> Dec 2026 | Trial primary completion date: Jan 2026 --> Jul 2026
    Enrollment change • Trial completion date • Trial primary completion date
    2ms
    Epinephrine-Added Irrigation Versus Intravenous Tranexamic Acid in Arthroscopic Rotator Cuff Repair: A Prospective Randomized Controlled Trial (clinicaltrials.gov)
    P=N/A, N=80, Completed, Saglik Bilimleri Universitesi
    New trial
    2ms
    The Effects of Tranexamic Acid on Joint Inflammation and Cartilage Health in Anterior Cruciate Ligament Injured Patients (clinicaltrials.gov)
    P2, N=50, Recruiting, Stanford University | Trial completion date: Jan 2026 --> Jan 2027 | Trial primary completion date: Jan 2026 --> Jan 2027
    Trial completion date • Trial primary completion date
    2ms
    Effects of Red and Infrared Photobiomodulation in Rhinoplasty at a Single Centre (clinicaltrials.gov)
    P=N/A, N=60, Recruiting, University of Nove de Julho | Not yet recruiting --> Recruiting | Trial completion date: Jul 2030 --> Nov 2030 | Initiation date: Oct 2025 --> Jan 2026
    Enrollment open • Trial completion date • Trial initiation date
    3ms
    Comparison of Anticoagulant Effects Between Nafamostat Mesylate and Sodium Citrate in Double Filtration Plasmapheresis (ChiCTR2600117445)
    P=N/A, N=140, Not yet recruiting, The First Affiliated Hospital of Army Medical University PLA; The First Affiliated Hospital of Army Medical University PLA
    New trial
    |
    nafamostat