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    DRUG CLASS:

    Steroid receptor agonist

    Related drugs:
    2d
    Comparison of Spinal Anesthesia Adjuvant and Quadratus Lumborum Block on the Opioid Requirement and Perioperative Pain of Laparoscopic Kidney Transplant Donor (clinicaltrials.gov)
    P=N/A, N=60, Completed, Indonesia University | Recruiting --> Completed
    Trial completion
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    dexamethasone injection
    5d
    Post-op Prednisone and Glucose Monitoring in TKA (clinicaltrials.gov)
    P4, N=104, Not yet recruiting, Columbia University
    New P4 trial
    |
    prednisone
    7d
    Case report: superficial kaposiform hemangioendothelioma without the Kasabach-Merritt phenomenon. (PubMed, Front Oncol)
    Upon confirming KHE diagnosis, we initiated a combined sirolimus and prednisone treatment. In this report, we also discuss the clinical manifestations, imaging features, histopathological characteristics, and treatment options for this KHE subtype and review relevant literature. This case highlights the diagnostic features and therapeutic considerations of superficial KHE without KMP, emphasizing the importance of multidisciplinary evaluation.
    Journal
    |
    CD34 (CD34 molecule) • CD31 (Platelet and endothelial cell adhesion molecule 1) • PECAM1 (Platelet And Endothelial Cell Adhesion Molecule 1) • SLC2A1 (Solute Carrier Family 2 Member 1)
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    prednisone • sirolimus
    9d
    Protective Effects of Adipose-derived Stem Cell Exosomes vs Dexamethasone on Neuromotor Deficits in Focal Cerebral Ischemia. (PubMed, Basic Clin Neurosci)
    Exosomes were administered intravenously, while dexamethasone was given intraperitoneally...Their multi-modal mechanisms-including anti-inflammatory, anti-apoptotic, angiogenic, and neuroregenerative effects-highlight their potential as a novel therapeutic approach for stroke management. Future research should focus on clinical translation, dosage optimization, and long-term safety evaluation.
    Journal
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    IL6 (Interleukin 6) • TNFA (Tumor Necrosis Factor-Alpha)
    |
    dexamethasone injection
    12d
    Dexamethasone for Ureteral STent Symptoms (DUSTS) (clinicaltrials.gov)
    P1/2, N=70, Recruiting, The Methodist Hospital Research Institute | Not yet recruiting --> Recruiting
    Enrollment open
    |
    dexamethasone injection
    12d
    Dexamethasone to Prevent Side Effects of Spinal Anesthesia in Cesarean Delivery (clinicaltrials.gov)
    P4, N=176, Enrolling by invitation, University Medical Center Ho Chi Minh City (UMC)
    New P4 trial • Adverse events
    |
    dexamethasone injection
    14d
    Pomalidomide Plus Anti-CD20 Antibody and Prednisone in Frontline Indolent B-Cell Lymphoma (clinicaltrials.gov)
    P=N/A, N=30, Not yet recruiting, The First Affiliated Hospital of Soochow University
    New trial
    |
    CD20 (Membrane Spanning 4-Domains A1)
    |
    CD20 positive
    |
    prednisone • pomalidomide
    14d
    Pathway-Specific Effects of Oral Corticosteroids on Eosinophilic Inflammation and Tissue Remodeling in Chronic Rhinosinusitis with Nasal Polyps. (PubMed, Int J Mol Sci)
    Sixty-five patients eligible for endoscopic sinus surgery (ESS) were enrolled and divided into two groups: Group 1 (n = 42) received topical steroids combined with oral prednisone (40 mg/day for 7 days preoperatively), whereas Group 2 (n = 23) received topical steroids alone...No significant differences were observed in IL-4 or TNF-α expression. These findings indicate that short-term OCSs selectively modulate molecular pathways associated with eosinophilic inflammation and tissue remodeling in CRSwNP, supporting biomarker-driven precision medicine strategies.
    Journal
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    TNFA (Tumor Necrosis Factor-Alpha) • CCL11 (C-C Motif Chemokine Ligand 11) • TGFB1 (Transforming Growth Factor Beta 1) • IL4 (Interleukin 4) • POSTN (Periostin)
    |
    prednisone
    18d
    Impact of Dexamethasone Route on Pain and Inflammation in iPACK With ACB for Knee Arthroplasty (clinicaltrials.gov)
    P4, N=90, Completed, Poznan University of Medical Sciences | Recruiting --> Completed | Trial completion date: Oct 2026 --> Mar 2026 | Trial primary completion date: Sep 2026 --> Mar 2026
    Trial completion • Trial completion date • Trial primary completion date
    |
    dexamethasone injection
    19d
    NeFRIN: Efficacy and Safety of Nefecon on Prevention of Relapse of IgA Nephropathy: a Randomized, Double-blinded, Placebo-Controlled Trial (clinicaltrials.gov)
    P4, N=288, Not yet recruiting, Nanfang Hospital, Southern Medical University
    New P4 trial
    19d
    The Effect of Dexamethasone Administration Route and Local Anesthetic Concentration on Pain, Inflammatory Response, and Neuromonitoring in Children Undergoing Scoliosis Correction (clinicaltrials.gov)
    P4, N=60, Recruiting, Poznan University of Medical Sciences | Trial completion date: Jan 2026 --> Sep 2026 | Trial primary completion date: Dec 2025 --> Jul 2026
    Trial completion date • Trial primary completion date
    |
    dexamethasone injection
    19d
    Perineural vs Intravenous Dexamethasone as an Adjuvant to Brachial Plexus Block in Pediatric Hand Surgery (clinicaltrials.gov)
    P=N/A, N=150, Recruiting, Poznan University of Medical Sciences | Not yet recruiting --> Recruiting | Initiation date: Apr 2026 --> Dec 2025
    Enrollment open • Trial initiation date
    |
    dexamethasone injection