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    DRUG CLASS:

    Steroid receptor agonist

    Related drugs:
    1d
    Dexamethasone for Ureteral STent Symptoms (DUSTS) (clinicaltrials.gov)
    P1/2, N=70, Not yet recruiting, The Methodist Hospital Research Institute | Trial completion date: Jan 2026 --> Apr 2027 | Initiation date: May 2025 --> Apr 2026 | Trial primary completion date: Dec 2025 --> Dec 2026
    Trial completion date • Trial initiation date • Trial primary completion date
    |
    dexamethasone injection
    4d
    Dextenza vs Prednisolone Acetate After Cataract Surgery for Patients With Diabetes (clinicaltrials.gov)
    P4, N=0, Withdrawn, Baylor Research Institute | N=200 --> 0 | Not yet recruiting --> Withdrawn
    Enrollment change • Trial withdrawal
    4d
    EXAFIP2: Glucocorticoids Versus Placebo for the Treatment of Acute Exacerbation of Idiopathic Pulmonary Fibrosis (clinicaltrials.gov)
    P3, N=110, Recruiting, Fondation Hôpital Saint-Joseph | Trial primary completion date: Oct 2025 --> Mar 2026
    Trial primary completion date
    |
    prednisone • methylprednisolone sodium succinate
    5d
    TKA: Oral vs Intravenous Dexamethasone in Total Knee Arthroplasty (clinicaltrials.gov)
    P=N/A, N=99, Not yet recruiting, Haseki Training and Research Hospital
    New trial
    |
    dexamethasone • dexamethasone injection
    7d
    Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstructive Sleep Apnea (clinicaltrials.gov)
    P=N/A, N=64, Not yet recruiting, Ain Shams University
    New trial
    |
    dexamethasone injection
    7d
    DARWIN: Study to Investigate Changes in Airway Inflammation, Symptoms, and Rescue Therapy Utilization With AIRSUPRA Compared to Albuterol as Needed in Adults With Mild Asthma (clinicaltrials.gov)
    P4, N=101, Completed, AstraZeneca | Active, not recruiting --> Completed
    Trial completion
    7d
    CORSAR: Evaluation of the Efficacy of Corticosteroids in Septic Arthritis in Adults (clinicaltrials.gov)
    P2, N=200, Not yet recruiting, Assistance Publique - Hôpitaux de Paris
    New P2 trial
    |
    prednisone
    8d
    Drugs Associated with Pediatric Cataracts: A Real-World Pharmacovigilance Study. (PubMed, Children (Basel))
    Difluprednate showed the highest pharmacovigilance signal (ROR: 963.67; 95% CI: 316.27-2936.31; n = 4). Notably, CFTR modulators exhibited striking signals: ivacaftor (ROR: 30.75; 95% CI: 18.06-52.37; n = 14), elexacaftor-ivacaftor-tezacaftor (ROR: 15.58; 95% CI: 9.86-24.63; n = 19), and ivacaftor-lumacaftor (ROR: 13.2; 95% CI: 7.9-22.07; n = 15). This study provides a comprehensive large-scale pharmacovigilance profile of drug-induced pediatric cataracts, identifying agents with high-risk pharmacovigilance signals and underscoring the need for proactive ocular monitoring. These findings can inform clinical decision making and prevention strategies and guide future mechanistic research.
    Journal • Adverse events • Real-world evidence
    |
    CFTR (CF Transmembrane Conductance Regulator)
    9d
    Effect of Perioperative Lidocaine or High-Dose Dexamethasone on Immune Response in Colon Cancer Surgery (PILDI Study) (clinicaltrials.gov)
    P2, N=2, Recruiting, Institute of Oncology Ljubljana
    New P2 trial
    |
    CXCL8 (Chemokine (C-X-C motif) ligand 8)
    |
    dexamethasone injection
    9d
    Taper Or Abrupt Steroid Stop: TOASSTtrial (clinicaltrials.gov)
    P4, N=530, Recruiting, University Hospital, Basel, Switzerland | Trial completion date: Dec 2026 --> Jun 2027 | Trial primary completion date: Dec 2026 --> Jun 2027
    Trial completion date • Trial primary completion date
    |
    prednisone
    14d
    Clinical Features and Treatment Outcomes of Patients with Tubulointerstitial Nephritis and Uveitis Syndrome: A Case Series. (PubMed, Ocul Immunol Inflamm)
    At baseline, all patients were managed with topical corticosteroids (TCS), with 6 (27%) patients requiring oral prednisone (PRD) and 17 (63%) steroid-sparing immunosuppressive therapy (SS-IMT)...Intermediate and posterior segment manifestations are common. Treatment with topical and systemic corticosteroids only may be insufficient to prevent disease relapse, with most patients requiring long-term immunosuppressive therapy.
    Journal
    |
    B2M (Beta-2-microglobulin)
    |
    prednisone
    16d
    PONV-DEX-GYN: Dexamethasone for Prevention of Postoperative Vomiting After Laparoscopic Gynecologic Surgery (clinicaltrials.gov)
    P=N/A, N=120, Completed, Rawalpindi Medical College
    New trial
    |
    dexamethasone injection