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LymphoTrack TRG Assay – MiSeq represents a significant improvement over existing clonality assays using fragment analysis as it efficiently detects the majority of TRG gene rearrangements using a single multiplex master mix, and at the same time identifies the DNA sequence specific for each clonal gene rearrangement. Therefore, this assay has two important and complementary uses: it both aids in the detection of initial clonal populations and identifies sequence information required to track those clones in subsequent samples.
Gene:
TRG (T Cell Receptor Gamma Locus)
Method:
Next-Generation Sequencing / PCR