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    TEST:
    OncoDEEP

    Company:
    OncoDNA
    Type:
    Laboratory Developed Test
    Related tests:
    OncoDEEP analyses solid biopsies by combining next-generation sequencing (313 genes), IHCs to study protein expression and additional tests. This complete tumour profiling allows to predict patient response to approved or experimental hormonal therapies, targeted drugs, immunotherapies and chemotherapies. The NGS panel is accurately designed according to oncologists’ needs in their current practice. Importantly, it includes an accurate determination of MSI, TMB and LOH. The NGS panel is regularly updated based on new findings reported in the literature in order to provide patients with the most cost-effective solution. NRTK testing is included in OncoDEEP for some cancer types and it can be ordered also as a standalone test.
    Cancer:
    Solid Tumor
    Gene:
    HRD (Homologous Recombination Deficiency), MSI (Microsatellite instability), TMB (Tumor Mutational Burden)
    Drug:
    5-fluorouracil, Alecensa (alectinib), Alunbrig (brigatinib), Erbitux (cetuximab), Gavreto (pralsetinib), Gilotrif (afatinib), Herceptin (trastuzumab), Kadcyla (ado-trastuzumab emtansine), Keytruda (pembrolizumab), Libtayo (cemiplimab-rwlc), Lorbrena (lorlatinib), Lynparza (olaparib), Mekinist (trametinib), Nerlynx (neratinib), Opdivo (nivolumab), Pemazyre (pemigatinib), Perjeta (pertuzumab), Piqray (alpelisib), Retevmo (selpercatinib), Rozlytrek (entrectinib), Tabrecta (capmatinib), Tafinlar (dabrafenib), Tagrisso (osimertinib), Tecentriq (atezolizumab), Vitrakvi (larotrectinib), Xalkori (crizotinib), Zykadia (ceritinib), anastrozole, capecitabine, epirubicin, erlotinib, everolimus, exemestane, gefitinib, gemcitabine, lapatinib, letrozole, pemetrexed, tamoxifen
    Method:
    Next-Generation Sequencing (NGS)