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BIOMARKER:
ALK rearrangement + BRCA2 F2801fs
i
Other names:
NBLST3, CD246, Anaplastic Lymphoma Kinase, Anaplastic Lymphoma Kinase (Ki-1), CD246 Antigen, Mutant Anaplastic Lymphoma Kinase, ALK, ALK Receptor Tyrosine Kinase, Anaplastic Lymphoma Receptor Tyrosine Kinase, ALK Tyrosine Kinase Receptor, BRCA2, BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, Breast cancer 2, early onset
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Entrez ID:
238
;
675
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
ALK positive (74)
ALK negative (4)
EGFR negative + ALK negative (4)
EGFR expression + ALK positive (3)
BRCA2 overexpression (2)
ALK expression + PDGFRA expression (1)
ALK expression + PDGFRB expression (1)
ALK overexpression (1)
ALK positive + ROS1 positive (1)
ALK positive + YAP1 overexpression (1)
ALK positive + YES1 overexpression (1)
KRT7 positive + NKX2-1 positive + ALK overexpression (1)
BRCA2 expression (1)
BRCA2 positive (1)
BRCA2 underexpression (1)
ALK positive (74)
ALK negative (4)
EGFR negative + ALK negative (4)
EGFR expression + ALK positive (3)
BRCA2 overexpression (2)
ALK expression + PDGFRA expression (1)
ALK expression + PDGFRB expression (1)
ALK overexpression (1)
ALK positive + ROS1 positive (1)
ALK positive + YAP1 overexpression (1)
ALK positive + YES1 overexpression (1)
KRT7 positive + NKX2-1 positive + ALK overexpression (1)
BRCA2 expression (1)
BRCA2 positive (1)
BRCA2 underexpression (1)
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ALK rearrangement + BRCA2 F2801fs
Lung Adenocarcinoma
ALK rearrangement + BRCA2 F2801fs
Lung Adenocarcinoma
olaparib + lorlatinib
Sensitive: C4 – Case Studies
olaparib + lorlatinib
Sensitive
:
C4
olaparib + lorlatinib
Sensitive: C4 – Case Studies
olaparib + lorlatinib
Sensitive
:
C4
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