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BIOMARKER:

MYC overexpression + IDH1 mutation

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Entrez ID:

Related biomarkers:

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IDH1 mutation + Chr del(1p) + Chr del(19q) (10)

BCL2 rearrangement + MYC amplification (2)

HR positive + MYC amplification (2)

MYC amplification + ALK F1174L (2)

MYC expression + MYC rearrangement (2)

MYC overexpression + IDH2 mutation (2)

MYC rearrangement + LDH elevation (2)

IDH1 mutation + BRAF V600E (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK1 fusion (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK2 fusion (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK3 fusion (2)

IDH1 mutation + NTRK1 fusion (2)

IDH1 mutation + NTRK2 fusion (2)

IDH1 mutation + NTRK3 fusion (2)

ALK fusion + MYC amplification + CCND1 deletion + FGFR3 deletion (1)

ALK positive + MYC amplification + CCND1 deletion (1)

EGFR T790M + MYC amplification (1)

HER-2 positive + MYC amplification (1)

HR positive + MYC mutation (1)

IDH1 mutation + MYC amplification + MAPRE1 overexpression (1)

IDH2 mutation + MYC amplification + MAPRE1 overexpression (1)

KIF5B-RET fusion + TP53 H193R + MYC amplification (1)

MYC amplification + BCL2 amplification + TNFRSF8 expression (1)

MYC mutation + ER positive (1)

miR-17-HG deletion + MYC positive (1)

IDH wild-type + FGFR3 S249C + TP53 V73fs (1)

IDH1 R132S + H3K27me3 loss + MET exon 14 skipping mutation (1)

IDH1 mutation + ATRX deletion + TP53 deletion (1)

IDH1 mutation + FGFR2 fusion (1)

IDH1 mutation + FGFR2 rearrangement (1)

IDH1 mutation + MGMT promoter methylation (1)

IDH1 mutation + TMB-L (1)

IDH1 mutation + WT1 overexpression (1)

IDH1 mutation + Chr del(1p) + Chr del(19q) + MGMT promoter methylation (0)

IDH1 mutation + Chr del(1p) + Chr del(19q) (10)

BCL2 rearrangement + MYC amplification (2)

HR positive + MYC amplification (2)

MYC amplification + ALK F1174L (2)

MYC expression + MYC rearrangement (2)

MYC overexpression + IDH2 mutation (2)

MYC rearrangement + LDH elevation (2)

IDH1 mutation + BRAF V600E (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK1 fusion (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK2 fusion (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK3 fusion (2)

IDH1 mutation + NTRK1 fusion (2)

IDH1 mutation + NTRK2 fusion (2)

IDH1 mutation + NTRK3 fusion (2)

ALK fusion + MYC amplification + CCND1 deletion + FGFR3 deletion (1)

ALK positive + MYC amplification + CCND1 deletion (1)

EGFR T790M + MYC amplification (1)

HER-2 positive + MYC amplification (1)

HR positive + MYC mutation (1)

IDH1 mutation + MYC amplification + MAPRE1 overexpression (1)

IDH2 mutation + MYC amplification + MAPRE1 overexpression (1)

KIF5B-RET fusion + TP53 H193R + MYC amplification (1)

MYC amplification + BCL2 amplification + TNFRSF8 expression (1)

MYC mutation + ER positive (1)

miR-17-HG deletion + MYC positive (1)

IDH wild-type + FGFR3 S249C + TP53 V73fs (1)

IDH1 R132S + H3K27me3 loss + MET exon 14 skipping mutation (1)

IDH1 mutation + ATRX deletion + TP53 deletion (1)

IDH1 mutation + FGFR2 fusion (1)

IDH1 mutation + FGFR2 rearrangement (1)

IDH1 mutation + MGMT promoter methylation (1)

IDH1 mutation + TMB-L (1)

IDH1 mutation + WT1 overexpression (1)

IDH1 mutation + Chr del(1p) + Chr del(19q) + MGMT promoter methylation (0)

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MYC overexpression + IDH1 mutation	Acute Myelogenous Leukemia	MYC overexpression + IDH1 mutation	Acute Myelogenous Leukemia	enasidenib Resistant: C3 – Early Trials enasidenib Resistant : C3	enasidenib Resistant: C3 – Early Trials enasidenib Resistant : C3
MYC overexpression + IDH1 mutation	Acute Myelogenous Leukemia	MYC overexpression + IDH1 mutation	Acute Myelogenous Leukemia	ivosidenib Resistant: C3 – Early Trials ivosidenib Resistant : C3	ivosidenib Resistant: C3 – Early Trials ivosidenib Resistant : C3