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our Premium Content: News alerts, weekly reports and conference plannersTEST:Archer® FusionPlex® Myeloid Kit
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Company:
Integrated DNA TechnologiesType:
Laboratory Developed Test
Related tests:
The Archer® FusionPlex® Myeloid Kit is a targeted next-generation sequencing assay to detect and identify fusions, point mutations and expression levels from 84 genes associated with myeloid-origin malignancies. Studies are performed from RNA extracted from several types of starting sample. Using Archer’s proprietary Anchored Multiplex PCR (AMP™)-based enrichment, fusions of all genes in this kit can be identified in a single sequencing assay, even without prior knowledge of fusion partners or breakpoints.
Cancer:
Acute Lymphocytic Leukemia, Chronic Myeloid Leukemia, Myelodysplastic Syndrome
Gene:
BCR (BCR Activator Of RhoGEF And GTPase), BRAF (B-raf proto-oncogene), CALR (Calreticulin), CBFB (Core-Binding Factor Subunit Beta 2), CBL (Cbl proto-oncogene), CEBPA (CCAAT Enhancer Binding Protein Alpha)
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BCR (BCR Activator Of RhoGEF And GTPase), BRAF (B-raf proto-oncogene), CALR (Calreticulin), CBFB (Core-Binding Factor Subunit Beta 2), CBL (Cbl proto-oncogene), CEBPA (CCAAT Enhancer Binding Protein Alpha), CHD1 (Chromodomain Helicase DNA Binding Protein 1), ETV6 (ETS Variant Transcription Factor 6), FGFR2 (Fibroblast growth factor receptor 2), FGFR3 (Fibroblast growth factor receptor 3), GATA1 (GATA Binding Protein 1), GATA2 (GATA Binding Protein 2), GLIS2 (GLIS Family Zinc Finger 2), GNAS (GNAS Complex Locus), IDH1 (Isocitrate dehydrogenase (NADP(+)) 1), IDH2 (Isocitrate Dehydrogenase (NADP(+)) 2), JAK1 (Janus Kinase 1), NRAS (Neuroblastoma RAS viral oncogene homolog), RARA (Retinoic Acid Receptor Alpha), ROS1 (Proto-Oncogene Tyrosine-Protein Kinase ROS)
Method:
Next-Generation Sequencing (NGS)