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our Premium Content: News alerts, weekly reports and conference plannersTEST:Archer® VariantPlex® Myeloid panel
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Company:
Integrated DNA TechnologiesType:
Laboratory Developed Test
Related tests:
The Archer® VariantPlex® Myeloid panel is a 75-gene targeted sequencing panel for AML, MPN, MDS and some Lymphoid malignancy markers. Powered by Anchored Multiplex PCR (AMP™) chemistry, this panel enables deep strand-specific amplification of molecular barcoded DNA fragments for sequencing. Archer® VariantPlex® kits are designed for the study of target genes from DNA extracted from several types of samples, and allow the detection of SNVs, indels and CNVs by means of the Archer Analysis software for the analysis and interpretation of the data.
Cancer:
Chronic Myeloid Leukemia
Gene:
ABL1 (ABL proto-oncogene 1), ASXL1 (ASXL Transcriptional Regulator 1), ATRX (ATRX Chromatin Remodeler), BCOR (BCL6 Corepressor), BRAF (B-raf proto-oncogene), CALR (Calreticulin)
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ABL1 (ABL proto-oncogene 1), ASXL1 (ASXL Transcriptional Regulator 1), ATRX (ATRX Chromatin Remodeler), BCOR (BCL6 Corepressor), BRAF (B-raf proto-oncogene), CALR (Calreticulin), CBL (Cbl proto-oncogene), EZH2 (Enhancer of zeste 2 polycomb repressive complex 2 subunit), FLT3 (Fms-related tyrosine kinase 3), GATA1 (GATA Binding Protein 1), GATA2 (GATA Binding Protein 2), GNAS (GNAS Complex Locus), HRAS (Harvey rat sarcoma viral oncogene homolog), IDH1 (Isocitrate dehydrogenase (NADP(+)) 1), IDH2 (Isocitrate Dehydrogenase (NADP(+)) 2), JAK2 (Janus kinase 2), JAK3 (Janus Kinase 3), KMT2A (Lysine Methyltransferase 2A), MYC (V-myc avian myelocytomatosis viral oncogene homolog), NF1 (Neurofibromin 1), NOTCH1 (Notch 1), NRAS (Neuroblastoma RAS viral oncogene homolog), PTEN (Phosphatase and tensin homolog), RAD21 (RAD21 Cohesin Complex Component), RUNX1 (RUNX Family Transcription Factor 1), SETBP1 (SET Binding Protein 1), SF3B1 (Splicing Factor 3b Subunit 1), SRSF2 (Serine and arginine rich splicing factor 2), STAG3 (Stromal Antigen 3), STAT3 (Signal Transducer And Activator Of Transcription 3), TP53 (Tumor protein P53), WT1 (WT1 Transcription Factor), XPO1 (Exportin 1)
Method:
Next-Generation Sequencing (NGS)