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our Premium Content: News alerts, weekly reports and conference plannersTEST:AVENIO Tumor Tissue Expanded Kit
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News alerts, weekly reports and conference planners
Company:
RocheType:
Research Use Only
Related tests:
The AVENIO Tumor Tissue Expanded Kit is an NGS assay for expanded profiling of solid tumors in formalin-fixed paraffin-embedded (FFPE) tissue samples. This assay contains 77 genes. It features all four mutation classes (SNVs, indels, fusions and CNVs) in a single DNA workflow with exceptional sensitivity and specificity. It has 99% success rate for FFPE tissue samples that pass input QC testing using the AVENIO QC kit included with the assay.
Cancer:
Solid Tumor
Gene:
ABL1 (ABL proto-oncogene 1), AKT1 (V-akt murine thymoma viral oncogene homolog 1), AKT2 (V-akt murine thymoma viral oncogene homolog 2), BRAF (B-raf proto-oncogene), BRCA1 (Breast cancer 1, early onset), BRCA2 (Breast cancer 2, early onset)
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ABL1 (ABL proto-oncogene 1), AKT1 (V-akt murine thymoma viral oncogene homolog 1), AKT2 (V-akt murine thymoma viral oncogene homolog 2), BRAF (B-raf proto-oncogene), BRCA1 (Breast cancer 1, early onset), BRCA2 (Breast cancer 2, early onset), CCND1 (Cyclin D1), CCND2 (Cyclin D2), CCND3 (Cyclin D3), CDK4 (Cyclin-dependent kinase 4), ER (Estrogen receptor), FGFR1 (Fibroblast growth factor receptor 1), FGFR2 (Fibroblast growth factor receptor 2), FGFR3 (Fibroblast growth factor receptor 3), FLT1 (Fms-related tyrosine kinase 1), FLT3 (Fms-related tyrosine kinase 3), FLT4 (Fms-related tyrosine kinase 4), IDH1 (Isocitrate dehydrogenase (NADP(+)) 1), IDH2 (Isocitrate Dehydrogenase (NADP(+)) 2), JAK2 (Janus kinase 2), JAK3 (Janus Kinase 3), KRAS (KRAS proto-oncogene GTPase), NRAS (Neuroblastoma RAS viral oncogene homolog), NTRK1 (Neurotrophic tyrosine kinase, receptor, type 1), PDGFRA (Platelet Derived Growth Factor Receptor Alpha), PDGFRB (Platelet Derived Growth Factor Receptor Beta), PTEN (Phosphatase and tensin homolog), RET (Ret Proto-Oncogene), SMO (Smoothened Frizzled Class Receptor), TP53 (Tumor protein P53)
Method:
Next-Generation Sequencing (NGS)