The AVENIO Tumor Tissue Surveillance Kit is an NGS assay that complements the AVENIO ctDNA Surveillance Kit designed for longitudinal monitoring of tumor burden, by establishing a baseline from formalin-fixed paraffin-embedded (FFPE) tissue samples. This assay contains 17 genes. It features all four mutation classes (SNVs, indels, fusions and CNVs) in a single DNA workflow with exceptional sensitivity and specificity. It has 99% success rate for FFPE tissue samples that pass input QC testing using the AVENIO QC kit included with the assay.
Cancer:
Colorectal Cancer
Gene:
ALK (Anaplastic lymphoma kinase), APC (APC Regulator Of WNT Signaling Pathway), BRAF (B-raf proto-oncogene), BRCA1 (Breast cancer 1, early onset), BRCA2 (Breast cancer 2, early onset), EGFR (Epidermal growth factor receptor)
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ALK (Anaplastic lymphoma kinase), APC (APC Regulator Of WNT Signaling Pathway), BRAF (B-raf proto-oncogene), BRCA1 (Breast cancer 1, early onset), BRCA2 (Breast cancer 2, early onset), EGFR (Epidermal growth factor receptor), HER-2 (Human epidermal growth factor receptor 2), KIT (KIT proto-oncogene, receptor tyrosine kinase), KRAS (KRAS proto-oncogene GTPase), NRAS (Neuroblastoma RAS viral oncogene homolog), PDGFRA (Platelet Derived Growth Factor Receptor Alpha), RET (Ret Proto-Oncogene), ROS1 (Proto-Oncogene Tyrosine-Protein Kinase ROS), TP53 (Tumor protein P53), UGT1A1 (UDP glucuronosyltransferase family 1 member A1)